Pregnancy associated plasma protein-A and epilepsy
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Dosyalar
Tarih
2007
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Tubitak Scientific & Technical Research Council Turkey
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, we aimed to investigate the role of pregnancy-associated plasma protein-A (PAPP-A) as insulin-like growth factor binding protein-4 (IGFBP-4) protease in epilepsy patients. We studied 16 epilepsy patients and 10 healthy controls. Serum PAPP-A levels of epilepsy patients (6.8 +/- 3.2 mU/L) were higher than of the control group (5.1 +/- 1.9 mU/L), but the difference was not statistically significant (P > 0.05). We concluded that PAPP-A may increase the bioavailability of insulin-like growth factors (IGFs) due to decreased neurogenesis and synthesis of IGFs in chronically epilepsy patients.
Açıklama
Coskun, Abdurrahman/0000-0002-1273-0604
WOS: 000254130800010
WOS: 000254130800010
Anahtar Kelimeler
brain tumor, epilepsy, IGF-I, IGFBP, ICFBP-4, neurogenesis, PAPP-A
Kaynak
Turkish Journal Of Medical Sciences
WoS Q Değeri
N/A
Scopus Q Değeri
Q3
Cilt
37
Sayı
1
