Predictors of adverse perinatal outcomes in intrahepatic cholestasis of pregnancy

Basit Öğe Kaydı
dc.contributor.authorÇelik, Samettin
dc.contributor.authorÇalışkan, Canan S.
dc.contributor.authorÇelik, Handan
dc.contributor.authorGüçlü, Mehmet
dc.contributor.authorBaşbuğ, Alper
dc.date.accessioned2020-04-30T23:21:22Z
dc.date.available2020-04-30T23:21:22Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000466963400008en_US
dc.descriptionPubMed: 31059115en_US
dc.description.abstractObjectives: Our objective was to evaluate in our clinic the perinatal outcomes of patients diagnosed with ICP based on pre-treatment maternal serum bile acid levels, attempt to identify the risk group and review the literature in light of this information. Material and methods: In total, 370 patients diagnosed with ICP were included in the study, divided into two groups based on the fasting total serum bile acid level before UDCA (Group 1: 10 >= 40 mu mol/L, and Group 2: >= 40 mu mol/L). The groups were examined for clinical characteristics and pregnancy outcomes. Results: It was found that preterm delivery and neonatal intensive care need increased at a serum bile acid cut-off value of 34 mu mol/L. Regardless of serum bile acid, significantly higher rates of meconium-stained amniotic fluid and foetal distress were observed in patients whose diagnoses were made before 34 weeks of gestation. Conclusions: Foetal complications over 40 mu mol/L of serum bile acid were significantly increased. However, slightly lower levels cut-off values (34 mu mol/L) were obtained in terms of preterm birth and neonatal intensive care need. The incidence of meconium-stained amniotic fluid and foetal distress was higher in patients whose diagnosis were made before 34 weeks of gestation.en_US
dc.identifier.doi10.5603/GP.2019.0039en_US
dc.identifier.endpage222en_US
dc.identifier.issn0017-0011
dc.identifier.issn2543-6767
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage217en_US
dc.identifier.urihttps://doi.org/10.5603/GP.2019.0039
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4182
dc.identifier.volume90en_US
dc.identifier.wosWOS:000466963400008en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofGinekologia Polskaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectintrahepatic cholestasisen_US
dc.subjectpregnancyen_US
dc.subjectperinatal complicationsen_US
dc.titlePredictors of adverse perinatal outcomes in intrahepatic cholestasis of pregnancyen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
4182.pdf
Boyut:
179.47 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu