Prophylactic Selective Laser Trabeculoplasty in the Prevention of Intraocular Pressure Elevation After Intravitreal Triamcinolone Acetonide Injection

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dc.contributor.authorBozkurt, Ercüment
dc.contributor.authorKara, Necip
dc.contributor.authorYazıcı, Ahmet Taylan
dc.contributor.authorYüksel, Kemal
dc.contributor.authorDemirok, Ahmet
dc.contributor.authorYılmaz, Ömer Faruk
dc.contributor.authorDemir, Şerif
dc.date.accessioned2020-04-30T23:21:47Z
dc.date.available2020-04-30T23:21:47Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionDemirok, Ahmet/0000-0001-8197-2458en_US
dc.descriptionWOS: 000297714900011en_US
dc.descriptionPubMed: 21861972en_US
dc.description.abstractPURPOSE: To evaluate the prophylactic efficacy of selective laser trabeculoplasty for preventing an increase in intraocular pressure (IOP) after intravitreal triamcinolone acetonide injection. DESIGN: Prospective, comparative, interventional case series. METHODS: We studied 31 eyes with a baseline TOP of 21 mm Hg or more of 31 patients for which intravitreal triamcinolone acetonide injection was planned for diabetic macular edema. The patients were divided into 2 groups, a study group and control group. The study group comprised 15 eyes of 15 patients that underwent selective laser trabeculoplasty a mean of 8.3 +/- 4.1 days before intravitreal triamcinolone acetonide injection. The control group comprised 16 eyes of 16 patients who underwent only intravitreal triamcinolone acetonide injection. Main outcomes measures were mean IOP and number of patients requiring antiglaucomatous therapy. RESULTS: Mean baseline IOP was 21.6 +/- 0.9 ram Hg in the study group and 21.5 +/- 0.8 mm Hg in the control group (P = .98). Mean IOP at 1 day after injection was 17.0 +/- 2.0 mm Hg in the study group and 19.5 +/- 4.3 mm Hg in the control group (P = .23). Mean IOP at 1 week after injection was 16.9 +/- 1.7 mm Hg and 18.4 +/- 4.0 mm Hg, respectively (P = .49); mean IOP at 1 month after injection was 16.4 +/- 1.5 mm Hg and 20.8 +/- 5.6 mm Hg, respectively (P = .003); mean IOP at 3 months after injection was 15.8 +/- 2.5 mm Hg and 18.3 +/- 5.5 mm Hg, respectively (P = .01); and mean IOP at 6 months after injection was 15.7 +/- 1.4 mm Hg and 17.1 +/- 1.5 mm Hg, respectively (P = .03). The number of patients requiring antiglaucomatous therapy during follow-up was 0 of 15 eyes in the study group and 8 of 16 eyes in the control group (P = .001). CONCLUSIONS: The IOP elevation after intravitreal triamcinolone acetonide injection may be prevented by performing selective laser trabeculoplasty before intravitreal triamcinolone acetonide injection, especially in cases with a baseline IOP of 21 mm Hg or more. (Am J Ophthalmol 2011;152:976-981. (C) 2011 by Elsevier Inc. All rights reserved.)en_US
dc.identifier.doi10.1016/j.ajo.2011.05.027en_US
dc.identifier.endpage981en_US
dc.identifier.issn0002-9394
dc.identifier.issn1879-1891
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage976en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajo.2011.05.027
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4251
dc.identifier.volume152en_US
dc.identifier.wosWOS:000297714900011en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofAmerican Journal Of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleProphylactic Selective Laser Trabeculoplasty in the Prevention of Intraocular Pressure Elevation After Intravitreal Triamcinolone Acetonide Injectionen_US
dc.typeArticleen_US

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