Sleep disorders in Behcet's disease, and their relationship with fatigue and quality of life

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dc.contributor.authorTaşçılar, Nida Fatma
dc.contributor.authorTekin, Nilgün
dc.contributor.authorAnkaralı, Handan
dc.contributor.authorSezer, Tuna
dc.contributor.authorAtik, Levent
dc.contributor.authorEmre, Ufuk
dc.contributor.authorÇınar, Fikret
dc.date.accessioned2020-04-30T23:31:59Z
dc.date.available2020-04-30T23:31:59Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.descriptionAnkarali, Handan Camdeviren/0000-0002-3613-0523; Tascilar, Nida/0000-0003-0780-0783en_US
dc.descriptionWOS: 000304191900007en_US
dc.descriptionPubMed: 22004346en_US
dc.description.abstractBehcets disease, a systemic vasculitis, can cause varying degrees of activity limitation, fatigue and quality of life impairment. To date, there have been no studies regarding sleep disturbance and its relationship with fatigue and life quality in Behcets disease. We aimed to evaluate sleep disorders and polysomnographic parameters, and to determine their relationship with fatigue and quality of life in Behcets disease. Fifty-one patients with Behcets disease without any neurological involvement were interviewed regarding sleep disorders. Twenty-one subjects with no sleep complaints were included as the control group. Sleep-related complaints were evaluated in a face-to-face interview. Sleep quality, excessive daytime sleepiness, fatigue, depression, anxiety, disease activity/severity, and quality of life questionnaires and an overnight polysomnography were performed. Prevalences of restless legs syndrome (35.3%) and obstructive sleep apnea syndrome with/without other sleep disorders (32.5%) were higher than in the control group and the general population. Fatigue was higher in patients with restless legs syndrome and obstructive sleep apnea syndrome, and in those with lower minimum oxygen saturation; hence, only patients with restless legs syndrome had quality of life impairment. Sleep efficiency index and sleep continuity index were lower, and wake after sleep onset, respiratory disturbance index and apneahypopnea index were higher than in controls (P < 0.01). Neither sleep disorders nor polysomnographic parameters were related to disease activity and severity. In conclusion, it is important to question sleep disorder followed by a polysomnography, if necessary, in order to improve quality of life and fatigue in Behcets disease.en_US
dc.identifier.doi10.1111/j.1365-2869.2011.00976.xen_US
dc.identifier.endpage288en_US
dc.identifier.issn0962-1105
dc.identifier.issue3en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage281en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2869.2011.00976.x
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4557
dc.identifier.volume21en_US
dc.identifier.wosWOS:000304191900007en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-Blackwellen_US
dc.relation.ispartofJournal Of Sleep Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBehcet's diseaseen_US
dc.subjectfatigueen_US
dc.subjectpolysomnographyen_US
dc.subjectquality of lifeen_US
dc.subjectrestless legs syndromeen_US
dc.subjectsleep apneaen_US
dc.titleSleep disorders in Behcet's disease, and their relationship with fatigue and quality of lifeen_US
dc.typeArticleen_US

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