Syntenic relationship of chromosomes in Strongyloides species and Rhabditophanes diutinus based on the chromosome-level genome assemblies
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Royal Soc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The Strongyloides clade, to which the parasitic nematode genus Strongyloides belongs, contains taxa with diverse lifestyles, ranging from free-living to obligate vertebrate parasites. Reproductive strategies are also diverse in this group of nematodes, employing not only sexual reproduction but also parthenogenesis, making it an attractive group to study genome adaptation to specific conditions. An in-depth understanding of genome evolution, however, has been hampered by fragmented genome assemblies. In this study, we generated chromosome-level genome assemblies for two Strongyloides species and the outgroup species Rhabditophanes diutinus using long-read sequencing and high-throughput chromosome conformation capture (Hi-C). Our synteny analyses revealed a clearer picture of chromosome evolution in this group, suggesting that a functional sex chromosome has been maintained throughout the group. We further investigated sex chromosome dynamics in the lifecycle of Strongyloides ratti and found that bivalent formation in oocytes appears to be important for male production in the mitotic parthenogenesis.This article is part of the Theo Murphy meeting issue 'Strongyloides: omics to worm-free populations'.
Açıklama
Anahtar Kelimeler
Strongyloides ratti, Hi-C, parthenogenesis, sex determination, sex chromosome evolution, Environmental Sex Determination, Chromatin Diminution, X-Chromosome, Reproduction, Evolution, Gametogenesis, Complement, Provides, Nematoda, Ratti
Kaynak
Philosophical Transactions of the Royal Society B-Biological Sciences
WoS Q Değeri
N/A
Scopus Q Değeri
Q1
Cilt
379
Sayı
1894
