Investigation of presence of beta-lactamases and susceptibilities to antibiotics in gram negative bacteria

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dc.contributor.authorÇalışkan, Emel
dc.contributor.authorÖztürk, C.E.
dc.contributor.authorAnkaralı, Handan
dc.date.accessioned2020-04-30T13:32:38Z
dc.date.available2020-04-30T13:32:38Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümüen_US
dc.description.abstractObjective:. In this study, beta-lactamase production and antibiotic susceptibility in some Gramnegative bacteria isolated in our hospital were investigated. Methods: The presence of inducible beta-lactamase by direct induction test, the presence of extended-spectrum beta-lactamase by double-disk synergy method were investigated. In-vitro susceptibility tests were performed by disk diffusion method, in the direction of the Clinical and Laboratory Standards Institute recommendations. Results: The rate of inducible beta-lactamase was found as 2 %, and the rate of extendedspectrum beta-lactamase as 8 %. Imipenem was the most effective antimicrobial. The rates of resistance to ampicillin, amoxicillin-clavulanic acid and ciprofloxacin were very high. Conclusion: Although, amikacin, gentamicin, sefoperazon-sulbactam, piperacillin-tazobactam can be used as alternatives to carbapenems in empirical treatment of nonserious infections in our hospital, ampicillin, amoxicillin-clavulanic acid and ciprofloxacin are not suitable for this purpose. © 2011 Düzce Medical Journal.en_US
dc.identifier.endpage17en_US
dc.identifier.issn1307671X
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage13en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/382
dc.identifier.volume13en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDuzce University Medical Schoolen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntibiotic resistance; ESBL; Gram-negative bacteria; IBLen_US
dc.titleInvestigation of presence of beta-lactamases and susceptibilities to antibiotics in gram negative bacteriaen_US
dc.title.alternativeGram negatif bakterilerde beta-laktamaz varlı?ının ve antibiyotik duyarlılıklarının araştırılmasıen_US
dc.typeArticleen_US

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