Investigation of presence of beta-lactamases and susceptibilities to antibiotics in gram negative bacteria
Küçük Resim Yok
Tarih
2011
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Duzce University Medical School
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective:. In this study, beta-lactamase production and antibiotic susceptibility in some Gramnegative bacteria isolated in our hospital were investigated. Methods: The presence of inducible beta-lactamase by direct induction test, the presence of extended-spectrum beta-lactamase by double-disk synergy method were investigated. In-vitro susceptibility tests were performed by disk diffusion method, in the direction of the Clinical and Laboratory Standards Institute recommendations. Results: The rate of inducible beta-lactamase was found as 2 %, and the rate of extendedspectrum beta-lactamase as 8 %. Imipenem was the most effective antimicrobial. The rates of resistance to ampicillin, amoxicillin-clavulanic acid and ciprofloxacin were very high. Conclusion: Although, amikacin, gentamicin, sefoperazon-sulbactam, piperacillin-tazobactam can be used as alternatives to carbapenems in empirical treatment of nonserious infections in our hospital, ampicillin, amoxicillin-clavulanic acid and ciprofloxacin are not suitable for this purpose. © 2011 Düzce Medical Journal.
Açıklama
Anahtar Kelimeler
Antibiotic resistance; ESBL; Gram-negative bacteria; IBL
Kaynak
Düzce Tıp Fakültesi Dergisi
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
13
Sayı
3
