Adding intrathecal morphine to unilateral spinal anesthesia results in better pain relief following knee arthroscopy

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dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorYücel, İstemi
dc.contributor.authorAkçalı, Gülgün Elif
dc.contributor.authorDeğirmenci, Erdem
dc.contributor.authorSezen, Gülbin
dc.contributor.authorİskender, Abdülkadir
dc.date.accessioned2020-04-30T22:39:00Z
dc.date.available2020-04-30T22:39:00Z
dc.date.issued2008
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000260955700005en_US
dc.descriptionPubMed: 19011774en_US
dc.description.abstractIntrathecal morphine is administered to provide profound and prolonged analgesia, and to treat acute postoperative pain. We compared the effectiveness of hyperbaric bupivacaine alone and in combination with morphine for unilateral spinal anesthesia in patients undergoing knee arthroscopy. Sixty patients were randomly allocated to two groups to receive either 1.2 ml (6 mg) of 0.5% hyperbaric bupivacaine (group B; n = 30) or 1.2 ml of 0.5% hyperbaric bupivacaine containing 0.16 mg of morphine (group BM; n = 30). Spinal block was assessed by pinprick and a modified Bromage scale and compared between the operated and nonoperated sides. Visual analog scale (VAS) values, duration of analgesia, and total analgesic requirement of patients were recorded. Patients in group BM had significantly lower VAS values on movement at 30 min and at 2, 4, 6, and 12 h postoperatively (P < 0.05 and P < 0.001, P < 0.001, P < 0.001, and P < 0.05, respectively). The total analgesic requirement in the first 24 h after surgery was significantly higher in group B (P < 0.001). Patients in group BM had a significantly longer duration of analgesia in the first 24 h postoperatively (P < 0.001). Motor blockade of the operated limb in group BM was similar to that in group B (P > 0.05), and motor blockade of the nonoperated limb in group BM was also similar to that in group B (P > 0.05). We conclude that unilateral spinal anesthesia with hyperbaric bupivacaine plus 0.16 mg morphine is preferable to hyperbaric bupivacaine alone with respect to analgesic requirement, duration of analgesia, and VAS values.en_US
dc.identifier.doi10.1007/s00540-008-0648-9en_US
dc.identifier.endpage372en_US
dc.identifier.issn0913-8668
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage367en_US
dc.identifier.urihttps://doi.org/10.1007/s00540-008-0648-9
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2555
dc.identifier.volume22en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Tokyoen_US
dc.relation.ispartofJournal Of Anesthesiaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMorphineen_US
dc.subjectIntrathecalen_US
dc.subjectUnilateralen_US
dc.subjectSpinal anesthesiaen_US
dc.titleAdding intrathecal morphine to unilateral spinal anesthesia results in better pain relief following knee arthroscopyen_US
dc.typeArticleen_US

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