Evaluation of Outcomes in Patients Given Dexmedetomidine in Functional Endoscopic Sinus Surgery

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dc.contributor.authorGüven, Damla Güçlü
dc.contributor.authorDemiraran, Yavuz
dc.contributor.authorSezen, Gülbin
dc.contributor.authorKepek, Ökkeş
dc.contributor.authorİskender, Abdülkadir
dc.date.accessioned2020-05-01T12:14:52Z
dc.date.available2020-05-01T12:14:52Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000295199700006en_US
dc.descriptionPubMed: 22032072en_US
dc.description.abstractObjectives: We aimed to evaluate the effects of dexmedetomidine hydrochloride (DEX) on hemodynamic parameters and on surgeon and patient satisfaction during functional endoscopic sinus surgery (FESS). Methods: Forty patients who were to undergo FESS were enrolled in this randomized, prospective, controlled study. In the DEX group, conscious sedation was induced with an infusion of 1 mu g/kg of DEX 10 minutes before surgery, followed by an infusion of DEX at 0.2 mu g/kg per hour. A control group was given identical amounts of saline solution. During the procedure, hemodynamic data were recorded. The patients evaluated their pain on a visual analog scale (VAS). Intraoperative bleeding was rated on a 6-point scale for evaluation of operative field visibility. Results: We observed that the DEX group had lower bleeding scores (p = 0.019). The heart rates were lower in the DEX group at the time of induction (p = 0.052) and in the 1st (p = 0.009) and 20th minutes (p = 0.039) of induction. The mean blood pressure values were lower in the DEX group in the 5th (p < 0.001), 45th (p = 0.003), and 60th (p = 0.05) minutes of induction. The VAS score was lower in the DEX group in the 30th postoperative minute (p = 0.001); however, the VAS score was lower in the control group after the 12th hour (p < 0.001). Postoperative side effects such as nausea, tachycardia, hypotension, and vomiting were significantly less frequent in the DEX group (p < 0.001). Conclusions: We observed that the intraoperative bleeding, hemodynamic stability, and VAS scores were better and the side effects were less frequent in the DEX group.en_US
dc.identifier.doi10.1177/000348941112000906en_US
dc.identifier.endpage592en_US
dc.identifier.issn0003-4894
dc.identifier.issue9en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage586en_US
dc.identifier.urihttps://doi.org/10.1177/000348941112000906
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6371
dc.identifier.volume120en_US
dc.identifier.wosWOS:000295199700006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherAnnals Publ Coen_US
dc.relation.ispartofAnnals Of Otology Rhinology And Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectdexmedetomidineen_US
dc.subjectFESSen_US
dc.subjectfunctional endoscopic sinus surgeryen_US
dc.subjecthemodynamic stabilityen_US
dc.subjectintraoperative bleedingen_US
dc.titleEvaluation of Outcomes in Patients Given Dexmedetomidine in Functional Endoscopic Sinus Surgeryen_US
dc.typeArticleen_US

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