Local control of primary oropharyngeal malignant melanomas with limited tissue excision: a report of three cases

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dc.contributor.authorÖztürk, Özcan
dc.contributor.authorCansız, Harun
dc.contributor.authorGüzel, M. Zeki
dc.contributor.authorKarakullukçu, Barış
dc.contributor.authorÖzek, Hüsnü
dc.date.accessioned2020-04-30T23:18:58Z
dc.date.available2020-04-30T23:18:58Z
dc.date.issued2005
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000227443000002en_US
dc.descriptionPubMed: 15455245en_US
dc.description.abstractMucosal malignant melanomas are rare lesions, and they have different characteristics from their cutaneous counterparts. Since extended excisions of mucosal malignant melanomas located in the oropharyngeal region cause significant morbidity, limited surgical excision comes into consideration. Three cases of extensive oropharyngeal malignant melanomas were resected with 0.5-1.5-cm healthy tissue margins. The cases were followed for local recurrences. Case 1 applied radiotherapy and chemotherapy in addition to immunotherapy, and the patient is still alive without any local recurrences 18 months after surgery. The patient in case 2 underwent radiotherapy and immunotherapy and died 6 months after surgery. The patient in case 3 received chemotherapy in addition to immunotherapy and died 12 months after surgery as a result of distant metastasis. All cases were without any local recurrences. Surgical excision with limited tumor-free tissue margins may be the surgery of choice to prevent morbidity associated with wide resection of oropharyngeal malignant melanomas if other authors also reconfirm these results with many more cases in the future.en_US
dc.identifier.doi10.1007/s00405-004-0748-6en_US
dc.identifier.endpage92en_US
dc.identifier.issn0937-4477
dc.identifier.issue2en_US
dc.identifier.startpage89en_US
dc.identifier.urihttps://doi.org/10.1007/s00405-004-0748-6
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3600
dc.identifier.volume262en_US
dc.identifier.wosWOS:000227443000002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Archives Of Oto-Rhino-Laryngologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmelanomaen_US
dc.subjectmucosaen_US
dc.subjectoropharynxen_US
dc.subjectlimited tissue excisionen_US
dc.subjectlocal controlen_US
dc.titleLocal control of primary oropharyngeal malignant melanomas with limited tissue excision: a report of three casesen_US
dc.typeArticleen_US

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