Bullous skin reaction seen after extravasation of calcium gluconate

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dc.contributor.authorCelbek, Gökhan
dc.contributor.authorGüngör, Adem
dc.contributor.authorAlbayrak, Hülya
dc.contributor.authorKır, Seher
dc.contributor.authorGüvenç, Serdar Cenk
dc.contributor.authorAydın, Yusuf
dc.date.accessioned2020-04-30T22:40:24Z
dc.date.available2020-04-30T22:40:24Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000314975800009en_US
dc.descriptionPubMed: 22830330en_US
dc.description.abstractIntravenous (IV) calcium is usually given to temporarily treat the effects of hyperkalaemia on muscle and heart. When extravasation of a calcium gluconate infusion occurs, there may be rapid and marked swelling and erythema, with signs of soft-tissue necrosis or infection, and ensuing extensive local calcification, called calcinosis cutis. We report a 26-year-old woman who was hospitalized for exacerbation of acute intermittent porphyria. She had a history of hypertension and chronic renal failure. On the second day of her hospitalization, she developed hyperpotassaemia (6.7mEq/L potassium; normal range 3.55mEq/L). She was given an IV infusion of 10mL calcium gluconate into the left dorsal pedal vein. Bullous skin reactions occurred in the infusion area nearly 2h after administration. The patient's leg was elevated and the lesions cleaned with 0.9% saline. By day 9 of hospitalization, the lesions had markedly regressed. Several drugs have been associated with dermoepidermal blistering as an adverse drug reaction, but there is only one existing report in the literature about this side-effect associated with calcium gluconate. Clinicians should be alert to the possibility of bullous skin reactions, which may be a predictor of extravasation and necrosis, when treating patients with IV calcium gluconate.en_US
dc.identifier.doi10.1111/j.1365-2230.2012.04436.xen_US
dc.identifier.endpage155en_US
dc.identifier.issn0307-6938
dc.identifier.issn1365-2230
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage154en_US
dc.identifier.urihttps://doi.org/10.1111/j.1365-2230.2012.04436.x
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2974
dc.identifier.volume38en_US
dc.identifier.wosWOS:000314975800009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofClinical And Experimental Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleBullous skin reaction seen after extravasation of calcium gluconateen_US
dc.typeArticleen_US

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