Increased P wave duration in patients with depression or anxiety disorder

Basit Öğe Kaydı
dc.contributor.authorKoçer, Emel
dc.contributor.authorAlçelik, Aytekin
dc.contributor.authorKoçer, Abdulkadir
dc.contributor.authorÖnder, Elif
dc.contributor.authorAtaoğlu, Ahmet
dc.date.accessioned2020-04-30T23:18:29Z
dc.date.available2020-04-30T23:18:29Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionKocer, Abdulkadir/0000-0003-2866-555X; Alcelik, Aytekin/0000-0002-3156-1076en_US
dc.descriptionWOS: 000277425100011en_US
dc.description.abstractBACKGROUND: Activation of the sympathetic nervous system plays an important role in regulating cardiovascular actions. P wave parameters can provide general information on central cardiovascular autonomic regulatory responses, which are altered in patients with anxiety disorders and depression. In particular, there are no reports addressing changes in P wave duration and dispersion. OBJECTIVE: To compare the differences in P wave duration and P wave dispersion between patients with anxiety disorders and depression, because patients with anxiety disorders and depression develop abnormal electrocardiograms. DESIGN, TIME AND SETTING: A non-randomized concurrent controlled study was performed. Patients with depression and general anxiety disorders were admitted at the psychiatry outpatient clinics of the Medical Faculty of Duzce University of Turkey between May 2005 and October 2006. PARTICIPANTS: A total of 71 consecutive patients with depression and anxiety disorders, as well as 50 physically and mentally healthy age-and gender-matched controls were selected. METHODS: Electrocardiogram records were obtained at the time of admission to the outpatient clinics. MAIN OUTCOME MEASURES: P wave duration and P wave dispersion were measured. RESULTS: Both the maximum (P-max) and minimum (P-min) P wave duration were greater in patients with psychiatric disorders than in healthy controls. P-max was significantly greater in patients with depression or anxiety disorders (Bonferroni test, P < 0.017). The P wave dispersion was similar between patients and controls (P > 0.017). P waves were similar between panic patients and other anxiety patients. Beck depression results were positively correlated with P-min and P-max (r = 0.374, 0.302, P = 0.013, 0.049, respectively), and not associated with P wave dispersion (P > 0.05). CONCLUSION: Psychiatric disorders are associated with increases in P-max, but not with P wave dispersion. The P wave changes were associated with the degree of depression.en_US
dc.identifier.doi10.3969/j.issn.1673-5374.2010.07.011
dc.identifier.endpage549en_US
dc.identifier.issn1673-5374
dc.identifier.issn1876-7958
dc.identifier.issue7en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage545en_US
dc.identifier.urihttps://doi.org/10.3969/j.issn.1673-5374.2010.07.011
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3345
dc.identifier.volume5en_US
dc.identifier.wosWOS:000277425100011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofNeural Regeneration Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectP waveen_US
dc.subjectdepressionen_US
dc.subjectanxietyen_US
dc.subjectpanic disorderen_US
dc.subjectscalesen_US
dc.subjectsympathetic modulationen_US
dc.subjectelectrocardiogramen_US
dc.subjectP wave durationen_US
dc.subjectP wave dispersionen_US
dc.titleIncreased P wave duration in patients with depression or anxiety disorderen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu