Significance of laboratory parameters in diagnosing acute appendicitis during pregnancy

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dc.authoridpeksöz, Rıfat/0000-0003-4658-5254
dc.authoridKORKUT, ERCAN/0000-0001-8543-7778
dc.authoriddişçi, esra/0000-0003-3657-3620
dc.authoridKaya, Abdulkadir/0000-0003-1725-1220
dc.authorwosidKaya, Abdulkadir/ADZ-2791-2022
dc.authorwosidpeksöz, Rıfat/AAG-1820-2021
dc.authorwosiddişçi, esra/GRS-0553-2022
dc.authorwosidKORKUT, ERCAN/GSE-3887-2022
dc.contributor.authorPeksöz, Rıfat
dc.contributor.authorDişçi, Esra
dc.contributor.authorKaya, Abdulkadir
dc.contributor.authorAğırman, Enes
dc.contributor.authorKorkut, Ercan
dc.contributor.authorAksungur, Nurhak
dc.contributor.authorAltundaş, Necip
dc.date.accessioned2023-07-26T11:50:29Z
dc.date.available2023-07-26T11:50:29Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Aile Hekimliği Ana Bilim Dalıen_US
dc.description.abstractBackground Acute appendicitis (AA) is the most frequently seen surgical emergency in pregnant women and the most frequently encountered cause of non-obstetric acute abdomen. Due to the physiological and anatomical changes that occur during pregnancy and the limited use of radiological methods, it is difficult to diagnose AA during pregnancy. These conditions increase the risk of morbidity and mortality; therefore, it is crucial to identify ideal laboratory markers that can be utilized to diagnose disease. Methods One hundred and ten pregnancies that fulfilled the inclusion criteria for AA diagnosis were retrospectively analysed between 2010 and 2021. Markers with high diagnostic values were discussed. Results The patients were divided into three groups as follows; Group I: negative appendectomy (n = 19); Group IIa: uncomplicated appendicitis (n = 59); Group IIb: complicated appendicitis (n = 32). There was no statistically significant difference in mean age or gestational week (P > 0.05). Group IIb had a higher rate of complications and a longer length of hospital stay (P < 0.05). There were significant differences between the groups in terms of white blood cell (WBC), neutrophil, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), C-reactive protein, lymphocyte-to- C-reactive protein ratio, total, direct, and indirect bilirubin values (P < 0.05). While platelet and lactate dehydrogenase (LDH) values did not differ substantially between groups, both were found to have a high diagnostic value. Conclusion It was concluded that WBC, neutrophil, NLR, PLR, total, direct and indirect bilirubin levels could be utilized to diagnose AA. Moreover, levels of WBC, neutrophil, NLR, platelet, PLR, LDH, total, direct and indirect bilirubin can be utilized to diagnose complicated appendicitis.en_US
dc.identifier.doi10.1111/ans.17443
dc.identifier.endpage127en_US
dc.identifier.issn1445-1433
dc.identifier.issn1445-2197
dc.identifier.issue1.Şuben_US
dc.identifier.pmid34967103en_US
dc.identifier.scopus2-s2.0-85122103117en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage121en_US
dc.identifier.urihttps://doi.org/10.1111/ans.17443
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12359
dc.identifier.volume92en_US
dc.identifier.wosWOS:000735910100001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorKaya, Abdulkadir
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofAnz Journal of Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectAcute Appendicitis; Diagnosis; Laboratory Parameters; Pregnancyen_US
dc.subjectAppendectomy; Hyperbilirubinemia; Lymphocyte; Management; Cohort; Impact; Ratio; Women; Risken_US
dc.titleSignificance of laboratory parameters in diagnosing acute appendicitis during pregnancyen_US
dc.typeArticleen_US

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