The Evaluation of Atherosclerosis in Migraine Patients

dc.contributor.authorBeşir, Fahri Halit
dc.contributor.authorKoçer, Abdulkadir
dc.contributor.authorDikici, Süber
dc.contributor.authorYazgan, Sibel
dc.contributor.authorÖzdem, Şeyma
dc.date.accessioned2020-04-30T23:33:38Z
dc.date.available2020-04-30T23:33:38Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionKocer, Abdulkadir/0000-0003-2866-555Xen_US
dc.descriptionWOS: 000312996400005en_US
dc.descriptionPubMed: 22524899en_US
dc.description.abstractA potential association might exist between atherosclerosis and migraine. Carotid intima-media thickness (CIMT) is a marker of generalized atherosclerosis; hence, we aimed to assess CIMT in migraine patients. This study included 30 patients and 60 healthy controls aged between 20 and 40 years. Episodic migraine diagnosis was made according to the criteria of International Headache Society (IHS). Healthy controls who do not suffer any headache problems were selected from among hospital and laboratory staffs. All subjects were evaluated regarding some parameters and features known to be associated with migraine and vascular changes, that is, gender, age, body mass index, blood pressure, cholesterol, smoking habits, used hormonal contraceptives, and history of disease. The left common carotid arteries of the subjects were examined, and CIMT was measured with real-time gray-scale sonography. Mean values and standard deviations were calculated. All measurements were made in migraine-free periods. Migraine patients and control subjects were well matched for those parameters known to be associated with vascular changes, that is, gender, age, BMI, blood pressure, and cholesterol. CIMT values were higher in patients. The results showed that the mean CCA IMT values were 0.493 +/- 0.074 mm and 0.409 +/- 0.053 mm in migraine patients and controls, respectively (P < 0.001). There is a relationship between atherosclerosis and inflammation in migraine patients. The risk of cranial inflammatory arteriopathy increases in repeated attacks of migraine. Our study also supports that high number of attacks and attack duration are important in the development of atherosclerosis.en_US
dc.identifier.doi10.1111/j.1533-2500.2012.00551.xen_US
dc.identifier.endpage45en_US
dc.identifier.issn1530-7085
dc.identifier.issn1533-2500
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage41en_US
dc.identifier.urihttps://doi.org/10.1111/j.1533-2500.2012.00551.x
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5014
dc.identifier.volume13en_US
dc.identifier.wosWOS:000312996400005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPain Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectmigraineen_US
dc.subjectatherosclerosisen_US
dc.subjectinflammationen_US
dc.subjectcarotid intima-media thicknessen_US
dc.titleThe Evaluation of Atherosclerosis in Migraine Patientsen_US
dc.typeArticleen_US

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