Evaluation of Osteoarticular Involvement Associated with Brucellosis in Children

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dc.contributor.authorKutlu Beseren, Tugba Nur
dc.contributor.authorBekis Bozkurt, Hayrunnisa
dc.contributor.authorErguven, Mueferet
dc.contributor.authorBicakci, Zafer
dc.date.accessioned2025-10-11T20:47:58Z
dc.date.available2025-10-11T20:47:58Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractAim: Brucellosis is a significant public health problem with high morbidity. Its most frequent complication is osteoarticular involvement. The study aimed to evaluate the relationship of osteoarticular involvement with clinical features and prognosis in children with brucellosis. Material and Methods: This retrospective study included pediatric patients between the ages of 1 and 18 years who were hospitalized and diagnosed with brucellosis between 2015 and 2020, and were regularly followed up. Aand all their findings and osteoarticular involvement data within the last two years were recorded. Clinical features, laboratory findings, osteoarticular involvement, and relapse rates of the patients were evaluated. Results: A total of 80 patients were included study. During the follow-up period, relapse developed in 14 (17.5%) patients. The most commonly affected joints were right (40%, n=32) and left (26.3%, n=21) hips, then right (27.5%, n=22) and left (23.8%, n=19) knees. Shoulder joint involvement rates and C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), alanine transaminase (ALT), and aspartate aminotransferase (AST) levels were statistically significantly higher in the relapse group (p=0.016, p=0.003, p=0.001, p<0.001, p<0.001, respectively). There was no significant difference in demographic characteristics, clinical features, and treatment responses of the patients between age groups, except weakness and sweating complaints that were high among older children (p=0.036). Conclusion: High admission ALT, AST, CRP, and ESR levels in brucellosis cases with osteoarticular involvement and the presence of shoulder joint involvement, albeit rarely, can be a warning sign in terms of relapse. Patients should be closely followed up in terms of brucellosis complications.en_US
dc.identifier.doi10.18678/dtfd.1579167
dc.identifier.endpage80en_US
dc.identifier.issn1307-671X
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-105006491503en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage75en_US
dc.identifier.trdizinid1310775en_US
dc.identifier.urihttps://doi.org/10.18678/dtfd.1579167
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1310775
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21656
dc.identifier.volume27en_US
dc.identifier.wosWOS:001484304100013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isodeen_US
dc.publisherDuzce Univ, Fac Medicineen_US
dc.relation.ispartofDuzce Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectBrucellosisen_US
dc.subjectosteoarthritisen_US
dc.subjectsacroiliac jointen_US
dc.subjectshoulder jointen_US
dc.subjectrelapseen_US
dc.titleEvaluation of Osteoarticular Involvement Associated with Brucellosis in Childrenen_US
dc.typeArticleen_US

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