Evaluation of the Indicators of Inflammation in Children and Adolescents with Attention Deficit and Hyperactivity Disorder: Effect of Sex and Subtype

Basit Öğe Kaydı
dc.contributor.authorAksu, Gülen Güler
dc.contributor.authorDağ, Pelin
dc.date.accessioned2023-04-10T20:19:31Z
dc.date.available2023-04-10T20:19:31Z
dc.date.issued2020
dc.departmentRektörlük, Rektörlüğe Bağlı Birimler, Düzce Üniversitesi Dergilerien_US
dc.description.abstractAim: It was aimed to evaluate the hematological inflammatory markers in treatment-naive andcomorbidity-free children and adolescents with attention deficit and hyperactivity disorder(ADHD) in this study.Material and Methods: One hundred sixty-nine children aged 6-18, who were diagnosed withADHD according to DSM-5 criteria were included in the study. Age and sex-matched 59healthy children without any psychiatric and/or medical disorder were included as a controlgroup. The children who had an intellectual disability and/or autism spectrum disorder, acute,chronic or inflammatory diseases were excluded from the study. Smoking, obesity and usingpsychotropic medications and lack of data in records were other exclusion criteria. ADHD andcontrol groups were compared in terms of sociodemographic characteristics, inflammatorymarkers and hematological parameters.Results: Mean platelet volume (MPV) and Basophil (BASO) levels were significantly higherin the ADHD group compared to the control group and this statistical difference was onlyobserved for boys. In hyperactivity subtype, red cell distribution width (RDW), lymphocyte(LYMPH) and monocytes (MONO) were higher; in attention deficit subtype mean plateletvolume-to-lymphocyte ratio (MPVLR) was higher than all other subtypes and control group.MPV was similar in three subtypes, and were higher in all of them than the control group.Conclusion: This study revealed that MPV and BASO tend to be higher in the ADHD groupespecially in boys. Hematological biomarkers may be useful for diagnosis of ADHD anddetermination of ADHD subtypes but data on this subject are insufficient and morecomprehensive studies are needed.en_US
dc.identifier.doi10.18678/dtfd.690128
dc.identifier.endpage90en_US
dc.identifier.issn1307-671X
dc.identifier.issue2en_US
dc.identifier.startpage84en_US
dc.identifier.trdizinid385795en_US
dc.identifier.urihttp://doi.org/10.18678/dtfd.690128
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/385795
dc.identifier.urihttps://hdl.handle.net/20.500.12684/11389
dc.identifier.volume22en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleEvaluation of the Indicators of Inflammation in Children and Adolescents with Attention Deficit and Hyperactivity Disorder: Effect of Sex and Subtypeen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
11389.pdf
Boyut:
433.31 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Düzce Tıp Fakültesi Dergisi Koleksiyonu