A Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitis

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dc.authorwosidCoşkun, Gökhan/HJY-0584-2023
dc.contributor.authorAkbaş, Türkay
dc.contributor.authorCoşkun, Gökhan
dc.contributor.authorTorun, Serkan
dc.contributor.authorAkın, Gül
dc.contributor.authorÖnbaş, Ömer
dc.date.accessioned2023-07-26T11:53:59Z
dc.date.available2023-07-26T11:53:59Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.description.abstractBackground: Invasive aspergillosis (IA) is an opportunistic infection generally encountered in patients with hematological malignancies. However, IA is increasingly recognized in non-neutropenic and critically ill patients in the absence of classic risk factors.Case Report: An 81-year-old man with diabetes mellitus (DM), chronic renal failure (CRF), and heart failure, who had had 1-week complaints of diarrhea, nausea, and vomiting, was admitted to the intensive care unit with septic shock, acute respi-ratory failure, and acute kidney injury. Chest computed tomography showed cavitary lung lesions and colonoscopy revealed ischemic ulcers in the descending colon. Other causes of cavitary lung lesions were excluded and all cultures were negative, except for bronchoalveolar lavage yielding Aspergillus fumigatus. Thus, Aspergillus fumigatus sepsis with multiorgan failures was diagnosed.Conclusion: Inhaled Aspergillus conidia are kept under control by alveolar macrophage. DM, CRF, and aging are the con-ditions that disrupt phagocytic activity of macrophages and predispose to IA.en_US
dc.identifier.doi10.14744/etd.2021.58812
dc.identifier.endpage620en_US
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue6en_US
dc.identifier.startpage618en_US
dc.identifier.urihttps://doi.org/10.14744/etd.2021.58812
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12681
dc.identifier.volume44en_US
dc.identifier.wosWOS:000885122500014en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorTürkay Akbaş
dc.institutionauthorGökhan Coşkun
dc.institutionauthorSerkan Torun
dc.institutionauthorGül Akın
dc.institutionauthorÖmer Önbaş
dc.language.isoenen_US
dc.publisherErciyes Univ Sch Medicineen_US
dc.relation.ispartofErciyes Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectCritically Ill Patient; Invasive Aspergillosis; Ischemic Colitis; Phagocytic Function; Sepsisen_US
dc.subjectInvasive Aspergillosis; Infections; Risken_US
dc.titleA Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitisen_US
dc.typeArticleen_US

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