A Critically Ill Patient with Aspergillus Fumigatus Sepsis-Related Ischemic Colitis
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Dosyalar
Tarih
2022
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erciyes Univ Sch Medicine
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: Invasive aspergillosis (IA) is an opportunistic infection generally encountered in patients with hematological malignancies. However, IA is increasingly recognized in non-neutropenic and critically ill patients in the absence of classic risk factors.Case Report: An 81-year-old man with diabetes mellitus (DM), chronic renal failure (CRF), and heart failure, who had had 1-week complaints of diarrhea, nausea, and vomiting, was admitted to the intensive care unit with septic shock, acute respi-ratory failure, and acute kidney injury. Chest computed tomography showed cavitary lung lesions and colonoscopy revealed ischemic ulcers in the descending colon. Other causes of cavitary lung lesions were excluded and all cultures were negative, except for bronchoalveolar lavage yielding Aspergillus fumigatus. Thus, Aspergillus fumigatus sepsis with multiorgan failures was diagnosed.Conclusion: Inhaled Aspergillus conidia are kept under control by alveolar macrophage. DM, CRF, and aging are the con-ditions that disrupt phagocytic activity of macrophages and predispose to IA.
Açıklama
Anahtar Kelimeler
Critically Ill Patient; Invasive Aspergillosis; Ischemic Colitis; Phagocytic Function; Sepsis, Invasive Aspergillosis; Infections; Risk
Kaynak
Erciyes Medical Journal
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
44
Sayı
6
