Ability of CHA2DS2-VASc/R2CHA2DS2-VASc Scores to Predict Complications Related to Cardiac Implantable Electronic Devices

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dc.authoridSoner, Serdar/0000-0002-2807-6424;
dc.contributor.authorSoner, Serdar
dc.contributor.authorAktan, Adem
dc.contributor.authorKilic, Raif
dc.contributor.authorGuzel, Hamdullah
dc.contributor.authorTastan, Ercan
dc.contributor.authorOksul, Metin
dc.contributor.authorComert, Adnan Duha
dc.date.accessioned2025-10-11T20:48:13Z
dc.date.available2025-10-11T20:48:13Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackgroundGlobally, the number of cardiac implantable electronic devices (CIEDs) is increasing. In our study, we aimed to investigate whether CHA(2)DS(2)-VASc and R(2)CHA(2)DS(2)-VASc scores are predictive of CIED-related complications. MethodsOur investigation was carried out with a multicenter retrospective design. Patients who underwent CIED surgery at two cardiac centers in Turkey between January 2011 and May 2023, 1676, were evaluated. The patients were divided into two groups according to their R(2)CHA(2)DS(2)-VASc scores. Patients with R(2)CHA(2)DS(2)-VASc >= 5 were included in group 1 (380 patients), and patients with R(2)CHA(2)DS(2)-VASc < 5 (1296 patients) were included in group 2. The primary outcome was defined as the cumulative events. Each component of cumulative events, such as hematoma, pericardial effusion, pneumothorax, and infection, was also defined as a secondary outcome. ResultsThe study's patient population had an average age of 62.9 +/- 14 years. Pneumothorax (1.8% vs. 1.3%, p = 0.444), pericardial effusion or tamponade (0.35% vs. 0.2%, p = 0.659), and clinically significant hematoma (1.1% vs. 0.6%, p = 0.376) were comparable between the groups. Infection-related devices and cumulative events classified as primary outcomes were higher in the R(2)CHA(2)DS(2)-VASc >= 5 group (6.1% vs. 1.2%, p < 0.001; 7.6% vs. 3.2%, p < 0.001, respectively). Modeling analyses showed that the CHA(2)DS(2)-VASc score and HT were also independent predictors of device-related infection and cumulative events. ConclusionIn the R(2)CHA(2)DS(2)-VASc >= 5 groups, infection related to the device system and cumulative events were higher. Patients with an R(2)CHA(2)DS(2)-VASc score of 5 or more and a high CHA(2)DS(2)-VASc score should be evaluated more carefully regarding infection and cumulative events before and after the operation.en_US
dc.identifier.doi10.1111/pace.15148
dc.identifier.endpage159en_US
dc.identifier.issn0147-8389
dc.identifier.issn1540-8159
dc.identifier.issue2en_US
dc.identifier.pmid39868985en_US
dc.identifier.scopus2-s2.0-85216200884en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage151en_US
dc.identifier.urihttps://doi.org/10.1111/pace.15148
dc.identifier.urihttps://hdl.handle.net/20.500.12684/21808
dc.identifier.volume48en_US
dc.identifier.wosWOS:001470331100017en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofPace-Pacingand Clinical Electrophysiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectcardiac implantable electronic deviceen_US
dc.subjectCHA(2)DS(2)-VASc Scoreen_US
dc.subjectcomplicationen_US
dc.subjectinfectionen_US
dc.subjectR(2)CHA(2)DS(2)-VASc scoreen_US
dc.titleAbility of CHA2DS2-VASc/R2CHA2DS2-VASc Scores to Predict Complications Related to Cardiac Implantable Electronic Devicesen_US
dc.typeArticleen_US

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