Relationship of Bone Densitometry and Bone Resorption Markers With Menopausal Type and Duration

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dc.contributor.authorAkdemir, Nermin
dc.contributor.authorBilir, Cemil
dc.contributor.authorCinemre, Hakan
dc.contributor.authorPekuz, Muhittin
dc.contributor.authorGökosmanoğlu, Feyzi
dc.date.accessioned2020-04-30T23:31:37Z
dc.date.available2020-04-30T23:31:37Z
dc.date.issued2010
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionBilir, Cemil/0000-0002-1372-4791en_US
dc.descriptionWOS: 000276859300005en_US
dc.description.abstractObjective: Menopause age and bone mineral density are positively related and there is a rapid bone loss in the early postmenopausal period. A ratio of 30% of post-menopausal women are affected from osteoporosis developing due to bone loss and this causes 40% risk of fracture in a 50-year old woman. Materials and Methods: In this sudy, serum osteocalcin and urine deoxypridinoline levels were analyzed in 102 postmenapausal and 48 healthy premenopausal controls who presented to gynecology outpatient clinic. Bone densitometry was obtained from all postmenopausal women. Postmenopausal patients were further divided into four groups according to time since menopause: <5 years, 5-9 years, 10-19 years and > 20 years. Results: Mean (SD) age in 48 premenopausal women was 47.7 (3.7) while it was 56.5 (6.8) in 102 post-menopausal women. 34 out of 102 post-menopausal women had surgical menopause due to bilateral oopheroctomy+hysterectomy while the remaining had natural menopause. No significant difference was found in bone-turnover markers between women with surgical and natural menopause. Conclusion: Although there was not a statistically significant difference between bone-turnover markers, bone mineral density stays lower in surgical menopausal patients and this difference disappear only after about 20 years. Also bone turnover markers are usually high up to five years after surgical menopause and return to normal levels after then. Thus, our study suggested that oopheroctomy does not cause additional risk to hysterectomy. We also suggest that there is not a longterm relationship between serum bone turnover markers or bone density and the etiology of menopause. (Turk J Rheumatol 2010; 25: 29-33)en_US
dc.identifier.endpage33en_US
dc.identifier.issn1309-0291
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage29en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4362
dc.identifier.volume25en_US
dc.identifier.wosWOS:000276859300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTurkish League Against Rheumatismen_US
dc.relation.ispartofTurkish Journal Of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSurgical menopauseen_US
dc.subjectnatural menopauseen_US
dc.subjectosteoporosisen_US
dc.titleRelationship of Bone Densitometry and Bone Resorption Markers With Menopausal Type and Durationen_US
dc.typeArticleen_US

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