Evaluation of mass mercury poisoning cases occurring in a center in Turkiye: symptomatology, treatment methods, and follow-up processes

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dc.authoridKURT, FATIH/0000-0003-1975-6492
dc.authorid, Mustafa Yildiz/0009-0007-4075-9854
dc.contributor.authorKurt, Fatih
dc.contributor.authorAkcil, Abdullah
dc.contributor.authorCangur, Sengul
dc.contributor.authorYildiz, Mustafa
dc.date.accessioned2025-10-11T20:48:46Z
dc.date.available2025-10-11T20:48:46Z
dc.date.issued2025
dc.departmentDüzce Üniversitesien_US
dc.description.abstractMercury (Hg) is a toxic heavy metal with extensive applications. In children, mercury exposure often occurs inadvertently through laboratories, thermometers, or fluorescent lamps. Inhalation of elemental mercury can affect the central nervous system and urinary system. Early diagnosis and treatment are crucial to prevent severe complications. A retrospective evaluation was conducted on 82 pediatric cases of mercury poisoning who presented to Bingol State Hospital on January 15, 2020. Blood and urine mercury levels were measured. Patients with mercury levels > 10 mu g/L received intravenous treatment with 2,3-dimercaptopropane sulfonic acid (DMPS) for 5 days. Plasma and urine mercury levels were analyzed before and after treatment. Adverse effects of treatment and follow-up processes were also examined. Of the patients, 43.9% were female, and 56.1% were male, with a mean age of 9.4 +/- 3.2 years. A total of 42.7% of cases were symptomatic, with headache being the most common symptom (26.8%). Significant reductions in blood and urine mercury levels were observed after treatment (p < 0.001). Adverse effects of the drug were reported in 43.9% of cases, with nausea (50%) and itching (25%) being the most frequent. Conclusion: Chelation therapy was effective in significantly reducing mercury levels in cases of mercury poisoning. Adverse effects must be carefully managed, and long-term follow-up is essential. This study provides significant contributions to the literature on mass mercury poisoning cases.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkiye (TUBIdot;TAK)en_US
dc.description.sponsorshipOpen access funding provided by the Scientific and Technological Research Council of Turkiye (TUB & Idot;TAK).en_US
dc.identifier.doi10.1007/s00431-025-06143-3
dc.identifier.issn0340-6199
dc.identifier.issn1432-1076
dc.identifier.issue5en_US
dc.identifier.pmid40266418en_US
dc.identifier.scopus2-s2.0-105003169495en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1007/s00431-025-06143-3
dc.identifier.urihttps://hdl.handle.net/20.500.12684/22097
dc.identifier.volume184en_US
dc.identifier.wosWOS:001473581900002en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofEuropean Journal of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmzKA_WOS_20250911
dc.subjectMercury poisoningen_US
dc.subjectDMPS (2,3-dimercaptopropane sulfonic acid)en_US
dc.subjectElemental mercuryen_US
dc.subjectUrine mercury levelen_US
dc.subjectBlood mercury levelen_US
dc.titleEvaluation of mass mercury poisoning cases occurring in a center in Turkiye: symptomatology, treatment methods, and follow-up processesen_US
dc.typeArticleen_US

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