Cystatin C Levels in Patients With Dipper and Nondipper Hypertension

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dc.contributor.authorOrdu, Serkan
dc.contributor.authorÖzhan, Hakan
dc.contributor.authorAlemdar, Recai
dc.contributor.authorYıldırım, Hayriye
dc.contributor.authorGüngör, Adem
dc.contributor.authorÇağlar, Sabri Onur
dc.contributor.authorBulur, Serkan
dc.date.accessioned2020-05-01T09:11:16Z
dc.date.available2020-05-01T09:11:16Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000301976100011en_US
dc.descriptionPubMed: 22373662en_US
dc.description.abstractObjective: Subjects with nondipper hypertension carry a higher risk of cardiovascular events than their normotensive counterparts. The present study was designed to investigate cystatin C levels in patients with dipper and nondipper hypertension. Methods: Eighty-eight consecutive patients who had been treated with antihypertensive drugs for at least 6 months were included in the study. Dipping and nondipping patterns were detected with ambulatory blood pressure monitoring. Clinical, laboratory, and ambulatory blood pressure monitoring data of patient groups with nondipper and dipper hypertension were compared. Results: Patients in the nondipper group were older than those in the dipper group. Serum cystatin C level was higher in the patients in the nondipper group. Cystatin C was negatively correlated with the rate of systolic blood pressure fall at night (r = -0.41; P < 0.001). Linear regression analyses revealed that only cystatin C level was a significant correlate of nocturnal systolic blood pressure decrease. Logistic regression analyses also showed that cystatin C was an independent predictor of nondipping pattern (odds ratio, 3.586; 95% confidence interval, 1.432-8.98; P = 0.006]). Conclusion: The present study showed that cystatin C is higher in patients with nondipper hypertension patients.en_US
dc.identifier.endpage679en_US
dc.identifier.issn1081-5589
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage676en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5450
dc.identifier.volume60en_US
dc.identifier.wosWOS:000301976100011en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherLippincott Williams & Wilkinsen_US
dc.relation.ispartofJournal Of Investigative Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcystatin Cen_US
dc.subjecthypertensionen_US
dc.subjectdippingen_US
dc.titleCystatin C Levels in Patients With Dipper and Nondipper Hypertensionen_US
dc.typeArticleen_US

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