Topical cyclosporine-A combined with mitomycin C for conjunctival and corneal squamous cell carcinoma
dc.contributor.author | Tunç, Murat | |
dc.contributor.author | Erbilen, Esin | |
dc.date.accessioned | 2020-04-30T23:34:52Z | |
dc.date.available | 2020-04-30T23:34:52Z | |
dc.date.issued | 2006 | |
dc.department | DÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü | en_US |
dc.description | WOS: 000241098900022 | en_US |
dc.description | PubMed: 17011863 | en_US |
dc.description.abstract | PURPOSE: To determine the efficiency of topical cyclosporine,A (CSA) combined with mitomycin C (MMC) as an adjunctive treatment in diffuse conjunctival and corneal squamous cell carcinoma (CCSC). DESIGN: Interventional case reports. METHODS: Two patients who had positive margins following surgical excision of CCSC were treated by topical CSA (0.05%) four times a day for 12 weeks, and topical MMC (0.01%) four times a day was combined with CSA at the second, fourth, and sixth weeks of the treatment. We controlled the tumor recurrence, vision, and ocular surface healing during the follow-up. RESULTS: There was no tumor recurrence during the follow up of 18 months. Limbal vascularization regressed considerably and the vision improved without any ocular surface problems in both patients. CONCLUSIONS: As an adjunctive treatment, topical CSA (0.05%) combined with MMC (0.01%), may prevent tumor recurrence and provide excellent ocular surface healing in diffuse CCSC. | en_US |
dc.identifier.doi | 10.1016/j.ajo.2006.05.003 | en_US |
dc.identifier.endpage | 675 | en_US |
dc.identifier.issn | 0002-9394 | |
dc.identifier.issue | 4 | en_US |
dc.identifier.startpage | 673 | en_US |
dc.identifier.uri | https://doi.org/10.1016/j.ajo.2006.05.003 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12684/5235 | |
dc.identifier.volume | 142 | en_US |
dc.identifier.wos | WOS:000241098900022 | en_US |
dc.identifier.wosquality | Q1 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Science Inc | en_US |
dc.relation.ispartof | American Journal Of Ophthalmology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/closedAccess | en_US |
dc.title | Topical cyclosporine-A combined with mitomycin C for conjunctival and corneal squamous cell carcinoma | en_US |
dc.type | Article | en_US |
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