Sleep habits of children diagnosed with attention/ deficit/ hyperactivity disorder and effects of treatment on sleep related parameters

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dc.authoridTufan, Evren/0000-0001-5207-6240
dc.authoridSarigedik, Enes/0000-0002-9294-1152
dc.authorwosidTufan, Evren/C-5074-2015
dc.authorwosidSarigedik, Enes/AAA-6569-2021
dc.contributor.authorYektas, Cigdem
dc.contributor.authorTufan, Ali Evren
dc.contributor.authorSarigedik, Enes
dc.date.accessioned2021-12-01T18:48:49Z
dc.date.available2021-12-01T18:48:49Z
dc.date.issued2020
dc.department[Belirlenecek]en_US
dc.description.abstractThis study aimed to evaluate the baseline sleep habits of children with ADHD and the effects of treatment with methylphenidate (MPH) and atomoxetine (ATX) on sleep parameters. Treatment naive children with clinically normal intelligence diagnosed with ADHD were enrolled in the study. Children were treated naturalistically with MPH and ATX. Treatments were started at 0.5 mg/ kg/ day and titrated weekly to a maximum of 1.2 mg/ kg/ day. The daily equivalent dose was calculated according to clinician toolkits of Utah Academy of Child and Adolescent Psychiatry. DSM-IV Based Screening and Assessment Scale for Disruptive Behavior Disorders- Parent form (DBSASDBD) and Clinical Global Impression Scale were used to assess ADHD symptoms and Children's Sleep Habits Questionnaire (CSHQ)- Short Form was used to assess the sleep habits and problems before and after the treatment. Both MPH and ATX reduced symptom severity of ADHD in all domains and also reduced total CSHQ scores with similar effect sizes. (0.7 for MPH vs. 0.8 for ATX). The rate of clinically significant sleep problems at baseline was 93.5 %. At the end-point, 83.9 % of the sample still displayed clinically significant sleep problems while none of the children were judged to have moderate-severe sleep problems. Our results suggest that both ATX and MPH may selectively improve different sleep domains in children with ADHD. Studies using standardized dosing schemes for longer durations and evaluating sleep with objective measurements may clarify the differential effects of treatments on sleep among children with ADHD.en_US
dc.identifier.doi10.1016/j.ajp.2020.102045
dc.identifier.issn1876-2018
dc.identifier.issn1876-2026
dc.identifier.pmid32361211en_US
dc.identifier.scopus2-s2.0-85083851580en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajp.2020.102045
dc.identifier.urihttps://hdl.handle.net/20.500.12684/10611
dc.identifier.volume52en_US
dc.identifier.wosWOS:000573651300010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevieren_US
dc.relation.ispartofAsian Journal Of Psychiatryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChildren's Sleep Habits Questionnaire (CSHQ)en_US
dc.subjectAttention deficit/ Hyperactivity Disorder (ADHD)en_US
dc.subjectMethylphenidateen_US
dc.subjectAtomoxetineen_US
dc.subjectDeficit/Hyperactivity Disorderen_US
dc.subjectMethylphenidateen_US
dc.subjectAtomoxetineen_US
dc.subjectAdhden_US
dc.subjectMetaanalysisen_US
dc.subjectAdolescentsen_US
dc.subjectReliabilityen_US
dc.subjectValidityen_US
dc.subjectVersionen_US
dc.subjectImpacten_US
dc.titleSleep habits of children diagnosed with attention/ deficit/ hyperactivity disorder and effects of treatment on sleep related parametersen_US
dc.typeArticleen_US

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