The prevalence of fibromyalgia among patients with hepatitis B virus infection

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dc.contributor.authorÖzşahin, Mustafa
dc.contributor.authorGönen, İbak
dc.contributor.authorErmiş, Fatih
dc.contributor.authorOktay, Murat
dc.contributor.authorBeşir, Fahri Halit
dc.contributor.authorKutlucan, Ali
dc.contributor.authorAtaoğlu, Safinaz
dc.date.accessioned2020-04-30T23:34:06Z
dc.date.available2020-04-30T23:34:06Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionoktay, murat/0000-0002-0893-4444en_US
dc.descriptionWOS: 000327587600011en_US
dc.descriptionPubMed: 24179575en_US
dc.description.abstractFibromyalgia (FM) is a syndrome characterized by widespread and chronic musculoskeletal pain, fatigue, morning stiffness, and sleep disturbance. However, the etiopathogenesis of FM remains unclear. Various etiological factors have been suggested to trigger FM. These include systemic rheumatismal disease, physical trauma, psychological disorders, and chronic infections. We determined the prevalence of FM in patients with chronic active hepatitis B virus (HBV) and inactive hepatitis B carriers, compared with matched healthy controls. Seventy-seven HBV patients (39 HBV carriers and 38 with chronic active hepatitis), were evaluated for FM syndrome. Seventy-seven HBsAg-negative healthy subjects were enrolled as a control group. We found that FM was very prevalent in patients with HBV infections (22% of the total). We found no difference in FM prevalence when patients with chronic active hepatitis B infections (21% FM prevalence) and those who were inactive hepatitis B carriers (23% FM prevalence) were compared. FM was not associated with the levels of HBV-DNA, ALT, or AST. Recognition and management of FM in HBsAg-positive patients will aid in improvement of quality-of-life. We fully accept that our preliminary results require confirmation in studies including larger numbers of patients. More work is needed to allow us to understand the role played by, and the relevance of, infections (including HBV) in FM syndrome pathogenesis.en_US
dc.identifier.endpage808en_US
dc.identifier.issn1940-5901
dc.identifier.issue9en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage804en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5103
dc.identifier.volume6en_US
dc.identifier.wosWOS:000327587600011en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherE-Century Publishing Corpen_US
dc.relation.ispartofInternational Journal Of Clinical And Experimental Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectFibromyalgiaen_US
dc.subjecthepatitis B virusen_US
dc.subjectinfectionen_US
dc.subjectprevalenceen_US
dc.titleThe prevalence of fibromyalgia among patients with hepatitis B virus infectionen_US
dc.typeArticleen_US

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