Amanitin and phallotoxin concentration in Amanita phalloides var. alba mushroom

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dc.contributor.authorKaya, Ertuğrul
dc.contributor.authorYılmaz, İsmail
dc.contributor.authorSinirlioğlu, Zeynep Aydın
dc.contributor.authorKarahan, Selim
dc.contributor.authorBayram, Recep
dc.contributor.authorYaykaşlı, Kürşat Oğuz
dc.contributor.authorSeveroğlu, Zeki
dc.date.accessioned2020-04-30T22:39:06Z
dc.date.available2020-04-30T22:39:06Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionYaykasli, Kursat/0000-0001-7550-6370; Saritas, Ayhan/0000-0002-4302-1093; Saritas, Ayhan/0000-0002-4302-1093; Kaya, Ertugrul/0000-0003-0081-682Xen_US
dc.descriptionWOS: 000328658600028en_US
dc.descriptionPubMed: 24139877en_US
dc.description.abstractAlthough rarely seen, Amanita phalloides var. alba, a variety of A. phalloides type mushrooms, causes mushroom poisoning resulting in death. Since it is frequently confused with some edible mushrooms due to its white colored cap and macroscopic appearance, it becomes important in toxicological terms. Knowledge of the toxin amount contained in this mushroom type is invaluable in the treatment of cases involving poisoning. In this study, we examined the toxin levels of various parts of the A. phalloides var. alba mushroom growing Duzce region of Turkey. Toxin analyses were carried out for A. phalloides var. alba, which were collected from the forests Duzce region of Turkey in 2011, as a whole and also separately in its spore, pileus, gills, stipe and volva parts. The alpha amanitin, beta amanitin, gamma amanitin, phalloidin and phallacidine analyses of the mushrooms were carried out using the RP-HPLC method. A genetic analysis of the mushroom showed that it had similar genetic characteristics as A. phalloides and was a variety of it. The lowest toxins quantity was detected in spores, volva and stipe among all parts of the mushroom. The maximum amount of amatoxins was measured in the gills. The pileus also contained a high amount of amatoxins. Generally, amatoxins and phallotoxin concentrations were lower as compared to A. phalloides, but interestingly all toxins other than gamma toxin were higher in the spores of A. phalloides var. alba. The amount of toxin in all of its parts had sufficient concentrations to cause death. With this study, the amatoxin and phallotoxin concentrations in A. phalloides var. alba mushroom and in its parts have been revealed in detail for the first time. (C) 2013 Elsevier Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.toxicon.2013.10.008en_US
dc.identifier.endpage233en_US
dc.identifier.issn0041-0101
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage225en_US
dc.identifier.urihttps://doi.org/10.1016/j.toxicon.2013.10.008
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2599
dc.identifier.volume76en_US
dc.identifier.wosWOS:000328658600028en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofToxiconen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAmanitinen_US
dc.subjectPhalloidinen_US
dc.subjectAmanita phalloides var. albaen_US
dc.subjectHPLCen_US
dc.titleAmanitin and phallotoxin concentration in Amanita phalloides var. alba mushroomen_US
dc.typeArticleen_US

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