The Use of Predictive Laboratory Tests in Rapid Triage of COVID-19 Pandemic Outpatient Clinic Patients

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dc.authoridÜnlü, Elif Nisa/0000-0002-4801-8854
dc.authorwosidÜnlü, Elif Nisa/HGD-6227-2022
dc.contributor.authorGamsızkan, Zerrin
dc.contributor.authorKaya, Abdulkadir
dc.contributor.authorDavran, Fatih
dc.contributor.authorÇalışkan, Emel
dc.contributor.authorÜnlü, Elif Nisa
dc.contributor.authorÜnal, Safa
dc.date.accessioned2023-07-26T11:51:30Z
dc.date.available2023-07-26T11:51:30Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Temel Tıp Bilimleri Bölümü, Tıbbi Mikrobiyoloji Ana Bilim Dalıen_US
dc.description.abstractBackground: Patients who come to the emergency pandemic outpatient clinic with a pre-diagnosis of COVID-19 are still a burden on the health system. Rapid triage of patients is important to reduce transmission. The aim of this study is to evaluate the biochemistry and hemogram results of real-time reverse transcription-polymerase chain reaction (RT-PCR) positive and negative patients in the emergency pandemic outpatient clinic and to investigate predictive values of the initial tests that will help to make rapid diagnosis. Methods: Patients who applied to the emergency pandemic outpatient clinic with the suspicion of COVID-19 be-tween November 01, 2020 and January 01, 2021 were evaluated with RT-PCR and laboratory examinations. Results: A total of 551 patients were included in the study. The mean age of the patients was 50.31 +/- 18.47 (min. 18 - max. 94), and 47.2% (n = 260) of the patients included in the study were male and 52.8% (n = 291) were female. In the comparison of hemogram parameters, we found that mean platelet volume (MPV) was significantly higher (p = 0.023), whereas white blood cell (WBC), platelet counts (PLT), lymphocyte and neutrophil values were significantly lower in RT-PCR positive patients (p < 0.001). There were no significant differences between the PCR positive and negative patients in terms of other parameters. In the comparison of biochemical parameters, we found that lactate dehydrogenase LDH (p = 0.001), creatinine (p = 0.002), and AST (p < 0.001) values were significantly higher in PCR positive patients, while there were no significant differences in terms of other biochemical parameters (p > 0.05). Conclusions: Our study results show that the practical quick-look hemogram and MPV can be used as a specially evaluated parameter in the rapid management of the first application COVID-19 patients. In addition, biochemically high levels of LDH and creatinine can be used to guide the clinician in terms of early hydration of the patient with a pre-diagnosis of COVID-19 to alleviate acute kidney damage.en_US
dc.identifier.doi10.7754/Clin.Lab.2021.210521
dc.identifier.endpage479en_US
dc.identifier.issn1433-6510
dc.identifier.issue3en_US
dc.identifier.pmid35254030en_US
dc.identifier.scopus2-s2.0-85125847851en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage472en_US
dc.identifier.urihttps://doi.org/10.7754/Clin.Lab.2021.210521
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12572
dc.identifier.volume68en_US
dc.identifier.wosWOS:000754670000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.institutionauthorGamsızkan, Zerrin
dc.institutionauthorKaya, Abdulkadir; Ünal, Safa
dc.institutionauthorDavran, Fatih
dc.institutionauthorÇalışkan, Emel
dc.institutionauthorÜnlü, Elif Nisa
dc.language.isoenen_US
dc.publisherClin Lab Publen_US
dc.relation.ispartofClinical Laboratoryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectCovid-19; Covid-19 Pandemic; Pandemic; Mpv; Triageen_US
dc.subjectPlatelet Counten_US
dc.titleThe Use of Predictive Laboratory Tests in Rapid Triage of COVID-19 Pandemic Outpatient Clinic Patientsen_US
dc.typeArticleen_US

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