Compare of optic coherence tomography parameters in recreational synthetic tetrahydrocannabinol use and healthy control

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dc.authoridTURAN SONMEZ, Feruza/0000-0001-8817-8521en_US
dc.authorscopusid57196037801en_US
dc.authorscopusid24399934200en_US
dc.authorscopusid58493417900en_US
dc.authorscopusid22833894000en_US
dc.authorscopusid55570222900en_US
dc.authorwosidTURAN SONMEZ, Feruza/B-8369-2017en_US
dc.contributor.authorEski, Mehmet Tahir
dc.contributor.authorTeberik, Kuddusi
dc.contributor.authorTaha, Sezer
dc.contributor.authorBuken, Bora
dc.contributor.authorSonmez, Feruza Turan
dc.date.accessioned2024-08-23T16:04:23Z
dc.date.available2024-08-23T16:04:23Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractPurposeTo evaluate retinal thickness (RT), retinal nerve fiber layer thickness (RNFLT), and choroidal thickness (CT) changes in synthetic cannabinoid (SC) users.MethodsThis prospective study evaluated the RT, RNFLT, and CT values of 56 SC users and 58 healthy controls. The individuals using SCs were referred to us by our hospital's forensic medicine department. Retinal and choroidal images were obtained using spectral-domain optical coherence tomography (OCT). Measurements (one subfoveal, three temporals, three nasal) were taken at 500 & mu;m intervals up to 1500 & mu;m using the caliper system. Only the right eye was used for subsequent analysis.ResultsMean ages were 27.7 & PLUSMN; 5.7 years in the SC-user group and 25.4 & PLUSMN; 6.7 in the control group. Subfoveal Global RNFLT was in the SCs group 102.3 & PLUSMN; 10.5 & mu;m and 105.6 & PLUSMN; 20.2 & mu;m in the control group (p = 0.271). Subfoveal CT was in the SC group mean of 316.1 & PLUSMN; 100.2 & mu;m and in the control group mean 346.4 & PLUSMN; 81.8 & mu;m (p = 0.065). RT, T500 (283.3 & PLUSMN; 36.7 & mu;m, 296.6 & PLUSMN; 20.5 & mu;m, p = 0.011) and N1500 (355.1 & PLUSMN; 14.3 & mu;m, 349.3 & PLUSMN; 18.1 & mu;m, p = 0.049) were significantly higher in the SC group than in the control group, respectively.ConclusionAnalysis of OCT findings of individuals who had been using SC for more than one year revealed no statistically significant difference between RNFLT and CT, although N1500 was significantly higher in RT. Further studies in the field of OCT are important to explore the pathology of SCen_US
dc.identifier.doi10.1080/15569527.2023.2234042
dc.identifier.endpage183en_US
dc.identifier.issn1556-9527
dc.identifier.issn1556-9535
dc.identifier.issue3en_US
dc.identifier.pmid37417942en_US
dc.identifier.scopus2-s2.0-85165192757en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage179en_US
dc.identifier.urihttps://doi.org/10.1080/15569527.2023.2234042
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14192
dc.identifier.volume42en_US
dc.identifier.wosWOS:001024610300001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofCutaneous And Ocular Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSynthetic cannabinoiden_US
dc.subjectretinal thicknessen_US
dc.subjectretinal nerve fiber layer (RNFL)en_US
dc.subjectchoroidal thicknessen_US
dc.subject>en_US
dc.subjectReceptoren_US
dc.subjectPharmacologyen_US
dc.subjectToxicologyen_US
dc.subjectSpiceen_US
dc.titleCompare of optic coherence tomography parameters in recreational synthetic tetrahydrocannabinol use and healthy controlen_US
dc.typeArticleen_US

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