Paraneoplastic Severe Sensorimotor Axonal Polyneuropathy in Pancreatic Neuroendocrine Carcinoma: A Case Report and Review of the Literature

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dc.contributor.authorAkbaş, Türkay
dc.contributor.authorCoşkun, Sinem Kantarcıoğlu
dc.contributor.authorTorun, Serkan
dc.contributor.authorÖztürk, Ayhan
dc.contributor.authorEsbah, Onur
dc.contributor.authorÖnbaş, Ömer
dc.date.accessioned2023-07-26T11:51:23Z
dc.date.available2023-07-26T11:51:23Z
dc.date.issued2022
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, İç Hastalıkları Ana Bilim Dalıen_US
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Nöroloji Ana Bilim Dalıen_US
dc.description.abstractObjective: Paraneoplastic neurological syndromes (PNSs) are a diverse group of neurological disorders affecting any part of the nervous system before or during cancer. Case: A 78-year-old man first experienced pain and burning in the upper extremity three years previously, to which muscle weakness was added a short time later. The same symptoms developed in the lower extremities one year previously. He was admitted to the intensive care unit due to pneumonia and was conscious but quadriplegic with a modified Rankin score of 5. Abdominal computed tomography showed mass lesions in the liver and pancreas. Biopsies revealed pancreatic small cell neuroendocrine carcinoma. Electrophysiological studies revealed severe sensorimotor axonal polyneuropathy. Paraneoplastic sensorimotor axonal polyneuropathy was diagnosed since other causes of polyneuropathy had been excluded. Palliative care was considered due to the patient's poor functional state. Conclusions: Early diagnosis of cancer is of paramount importance in patients with PNSs if appropriate treatment is to be provided.en_US
dc.identifier.doi10.18521/ktd.1019045
dc.identifier.endpage428en_US
dc.identifier.issn1309-3878
dc.identifier.issue2en_US
dc.identifier.startpage424en_US
dc.identifier.urihttps://doi.org/10.18521/ktd.1019045
dc.identifier.urihttps://hdl.handle.net/20.500.12684/12550
dc.identifier.volume14en_US
dc.identifier.wosWOS:000821703000020en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.institutionauthorÖnbaş, Ömer
dc.institutionauthorAkbas, Turkay
dc.institutionauthorCoşkun, Sinem Kantarcıoğlu
dc.institutionauthorTorun, Serkan
dc.institutionauthorÖztürk, Ayhan
dc.institutionauthorEşbah, Onur
dc.language.isoenen_US
dc.publisherDuzce Univ, Fac Medicineen_US
dc.relation.ispartofKonuralp Tip Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz$2023V1Guncelleme$en_US
dc.subjectNeuroendocrine Carcinoma; Quadriplegia; Ki67; Paraneoplastic Neurological Syndromesen_US
dc.subjectPrognostic-Factors; Neoplasmsen_US
dc.titleParaneoplastic Severe Sensorimotor Axonal Polyneuropathy in Pancreatic Neuroendocrine Carcinoma: A Case Report and Review of the Literatureen_US
dc.typeReview Articleen_US

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