Evaluation of left atrial mechanical functions and atrial conduction abnormalities in patients with clinical hypothyroid

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dc.contributor.authorÖztürk, Serkan
dc.contributor.authorDikbaş, Oğuz
dc.contributor.authorÖzyaşar, Mehmet
dc.contributor.authorAyhan, Selim
dc.contributor.authorÖzlü, Fatih
dc.contributor.authorBaltacı, Davut
dc.contributor.authorYazıcı, Mehmet
dc.date.accessioned2020-05-01T12:15:32Z
dc.date.available2020-05-01T12:15:32Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAlcelik, Aytekin/0000-0002-3156-1076en_US
dc.descriptionWOS: 000307428200010en_US
dc.descriptionPubMed: 22641548en_US
dc.description.abstractBackground: The aim of this study was to investigate left atrial (LA) mechanical functions, atrial electromechanical delay and P wave dispersion in hypothyroid patients. Methods: Thirty-four patients with overt hypothyroid and thirty controls were included. A diagnosis of overt hypothyroid was reached with increased serum TSH and decreased free T4 (fT4) levels. LA volumes were measured using the biplane area length method and LA active and passive emptying volumes and fraction were calculated. Intra- and interatrial electromechanical delay (EMD) were measured by tissue Doppler imaging (TDI). P wave dispersion was calculated by 12 lead electrocardiograms. Results: LA diameter were significantly higher in patients with overt hypothyroid (p = 0.021). LA passive emptying volume and LA passive emptying fraction were significantly decreased with hypothyroid patients (p = 0.002 and p < 0.001). LA active emptying volume and LA active emptying fraction were significantly increased with hypothyroid patients (p < 0.001 and p < 0.001). Infra- and interatrial EMD, were measured significantly higher in hypothyroid patients (30.6 +/- 6.1 vs 18.0 +/- 2.7, p < 0.001; and 10.6 +/- 3.4 vs 6.9 +/- 1.4, p < 0.001, respectively). P wave dispersion were significantly higher in hypothyroid patients (48.8 +/- 6.2 vs 44.3 +/- 7.2, p = 0.022). In stepwise regression analysis demonstrated that, interatrial EMD and LA active emptying fraction related with TSH and fT4. Conclusions: This study showed that impaired LA mechanical and electromechanical function in hypothyroid patients. TSH and T4 were independent determinant of interatrial EMD and LA active emptying fraction. (Cardiol J 2012; 19, 3: 287-294)en_US
dc.identifier.doi10.5603/CJ.2012.0051en_US
dc.identifier.endpage294en_US
dc.identifier.issn1897-5593
dc.identifier.issn1898-018X
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage287en_US
dc.identifier.urihttps://doi.org/10.5603/CJ.2012.0051
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6396
dc.identifier.volume19en_US
dc.identifier.wosWOS:000307428200010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherVia Medicaen_US
dc.relation.ispartofCardiology Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectatrial functionsen_US
dc.subjectinteratrial delayen_US
dc.subjectthyroid hormonesen_US
dc.titleEvaluation of left atrial mechanical functions and atrial conduction abnormalities in patients with clinical hypothyroiden_US
dc.typeArticleen_US

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