Long length of stay in the ICU associates with a high erythrocyte transfusion rate in critically ill patients

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dc.contributor.authorAkbaş, Türkay
dc.date.accessioned2020-04-30T23:18:59Z
dc.date.available2020-04-30T23:18:59Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAkbas, Turkay/0000-0002-2150-6866en_US
dc.descriptionWOS: 000473513700014en_US
dc.descriptionPubMed: 30859888en_US
dc.description.abstractObjective This study aimed to evaluate epidemiology and outcome among critically ill patients under a restrictive transfusion practice. Methods One hundred sixty-nine patients who were admitted to the intensive care unit (ICU) between March 2016 to December 2017 and remained in the ICU > 24 hours were retrospectively included. Results Hemoglobin levels on admission were <12 g/dL in 85% and <9 g/dL in 37.9% of patients. The median admission hemoglobin level was decreased on the last day of the ICU stay. Erythrocyte transfusion was required for 34% of patients. Transfused patients had high Acute Physiology and Chronic Health Evaluation II and Sequential Organ Failure Assessment scores, more requirement for invasive mechanical ventilation, vasopressors, and dialysis, long ICU and hospital stays, low hemoglobin levels, and high hospital and ICU mortality rates. Multivariate analysis showed that the likelihood of transfusion increased from 6.6 to 25.8 fold when the ICU stay extended from >= 7 to >= 15 days. Age, vasopressor use, dialysis, and erythrocyte transfusion >= 5 units were predictors of mortality. Conclusion Patients receiving transfusion are severely ill and have more life support therapies. The number of erythrocyte units transfused, age, and organ support therapies are independent predictors of mortality.en_US
dc.identifier.doi10.1177/0300060519832458en_US
dc.identifier.endpage1957en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue5en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1948en_US
dc.identifier.urihttps://doi.org/10.1177/0300060519832458
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3605
dc.identifier.volume47en_US
dc.identifier.wosWOS:000473513700014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal Of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnemiaen_US
dc.subjectintensive care unit (ICU)en_US
dc.subjectmortalityen_US
dc.subjectred blood cell transfusionen_US
dc.subjectsequential organ failure assessment (SOFA) scoreen_US
dc.subjectdialysisen_US
dc.subjectvasopressoren_US
dc.titleLong length of stay in the ICU associates with a high erythrocyte transfusion rate in critically ill patientsen_US
dc.typeArticleen_US

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