First isolation of a probiotic candidate Enterococcus mundtii from Herniaria glabra L. and evaluation of its wound healing activity

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dc.authoridugras, serpil/0000-0002-1867-5781en_US
dc.authoridFIDAN, AYSENUR/0000-0003-3188-266Xen_US
dc.authorscopusid58661467300en_US
dc.authorscopusid54397548800en_US
dc.authorwosidugras, serpil/KSM-3256-2024en_US
dc.contributor.authorFidan, Aysenur
dc.contributor.authorUgras, Serpil
dc.date.accessioned2024-08-23T16:04:20Z
dc.date.available2024-08-23T16:04:20Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractIn this study focused on probiotic properties of bacterium isolated from Herniaria glabra L. is a medicinal plant. The bacterium was isolated from H. glabra, and it was identified using the molecular method as Enterococcus mundtii AF-1 strain. Antibiotic sensitivity tests showed that AF-1 strain was sensitive to streptomycin, tobramycin, gentamicin, imipenem, erythromycin, and ciprofloxacin. The strain exhibited gamma-haemolytic activity. These results show that the strain can be considered safe. The AF-1 strain showed inhibitory activity against some pathogens, including Bacillus subtilis, Klebsiella pneumoniae, and Yersinia pseudotuberculosis. Additionally, AF-1 strain exhibited high tolerance to low pH, pepsin, pancreatin, and bile salts. These properties showed that the strain may survival under the gastrointestinal conditions. The strain showed 40% DPPH free radical scavenging activity. The autoaggregation rate of the strain was 72.46% and the strain exhibited the high coaggregation rate (70.77% with Escherichia coli, and 63.78% with Listeria monocytogenesis). AF-1 strain showed 38.10% adhesion towards n-hexane, and 47.62% adhesion toward chloroform. It has been found to have moderate hydrophobicity. These results demonstrated the beneficial colonization ability of the strain in the gut. Furthermore, it was observed that living cells of AF-1 strain showed healing activity in the artificial wound area. Result of studies, it is seen that AF-1 strain might be excellent a probiotic candidate. In this study focused on probiotic properties of bacterium isolated from Herniaria glabra L. is a medicinal plant.en_US
dc.identifier.doi10.1093/femsle/fnad083
dc.identifier.issn0378-1097
dc.identifier.issn1574-6968
dc.identifier.pmid37591672en_US
dc.identifier.scopus2-s2.0-85174751792en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1093/femsle/fnad083
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14172
dc.identifier.volume370en_US
dc.identifier.wosWOS:001087785400001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherOxford Univ Pressen_US
dc.relation.ispartofFems Microbiology Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectaggregationen_US
dc.subjectantioxidanten_US
dc.subjectEnterococcus mundtiien_US
dc.subjectHerniaria glabraen_US
dc.subjectprobioticsen_US
dc.subjectwound healing activityen_US
dc.subjectIn-Vitroen_US
dc.subjectLactobacillus Strainsen_US
dc.subjectFaecalisen_US
dc.subjectHydrophobicityen_US
dc.subjectIdentificationen_US
dc.subjectAdherenceen_US
dc.subjectBacteriumen_US
dc.subjectAdhesionen_US
dc.subjectCellsen_US
dc.titleFirst isolation of a probiotic candidate Enterococcus mundtii from Herniaria glabra L. and evaluation of its wound healing activityen_US
dc.typeArticleen_US

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