DES-based vortex-assisted liquid-liquid microextraction procedure developed for the determination of paraben preservatives in mouthwashes
Yükleniyor...
Dosyalar
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A green deep eutectic solvent-based vortex-assisted liquid-liquid microextraction (DES-VALLME) procedure for the determination of parabens in mouthwashes was developed. Deep eutectic solvents formed by combining DLmenthol and decanoic acid in different mol ratios were prepared, the highest extraction recovery was obtained with DES consisting of 4:1 M ratio, and this DES was used as an extraction solvent for paraben determination in mouthwashes. The effect of parameters such as solution pH, mol ratio of DES composition, DES volume, vortex and centrifugation time and sample volume were examined. Optimum working conditions of the study; 400 mu L DES, 3 min. vortex time, 5 min. centrifugation time, 5 mL sample volume were determined. The detection limit was in the range of 4.6-6.1 mu g L-1, while the RSDs values were in the range of 0.70-1.41% in intraday and 1.27-2.41% in interday. The method in the study was successfully applied for the determination of methyl, ethyl, propyl and butyl paraben in 10 different mouthwashes obtained from cosmetic stores..
Açıklama
Anahtar Kelimeler
Parabens; Green Chemistry; Microextraction; Deep Eutectic Solvent; Preservatives; Mouthwash, Deep Eutectic Solvent; Solid-Phase Microextraction; Personal Care Products; Gas-Chromatography; Extraction; Preconcentration; Absorption; Dispersion; Separation; Beverages
Kaynak
Microchemical Journal
WoS Q Değeri
Q1
Scopus Q Değeri
Q1
Cilt
179
