Gastroesophageal reflux in asymptomatic obese subjects: An esophageal impedance-pH study

dc.contributor.authorAkyüz, Filiz
dc.contributor.authorUyanıkoğlu, Ahmet
dc.contributor.authorErmiş, Fatih
dc.contributor.authorArıcı, Serpil
dc.contributor.authorAkyüz, Ümit
dc.contributor.authorBaran, Bülent
dc.contributor.authorGül, Nurdan
dc.date.accessioned2020-05-01T12:10:09Z
dc.date.available2020-05-01T12:10:09Z
dc.date.issued2015
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionBaran, Bulent/0000-0001-7966-2346; Uyanikoglu, Ahmet/0000-0003-4881-5244en_US
dc.descriptionWOS: 000350689100021en_US
dc.descriptionPubMed: 25780302en_US
dc.description.abstractAIM: To investigate the relationship between reflux and body mass index (BMI) in the asymptomatic obese population using the impedance-pH technique. METHODS: Gastroesophageal reflux is frequent in the obese population. However, the relationship between acid reflux and BMI in asymptomatic obese people is unclear. Forty-six obese (BMI > 25 kg/m(2)) people were enrolled in this prospective study. We evaluated the demographic findings and 24-h impedance pH values of the whole group. Gas, acid (pH < 4), weak acid (pH = 4-7) and weak alkaline (pH = 7) reflux parameters were analyzed. RESULTS: The mean age of patients was 49.47 +/- 12.24 years, and half of them were men. The mean BMI was 30.64 +/- 3.95 kg/m(2) (25.14-45.58 kg/m(2)). BMI of 23 was over 30 kg/m(2). Seventeen patients had a comorbidity (hypertension, diabetes mellitus, or ischemic heart disease). Endoscopic examination revealed esophagitis in 13 of the 28 subjects (10 Grade A, 3 Grade B). The subjects were divided into two groups according to BMI (< 30 and > 30 kg/m(2)). Demographic and endoscopic findings, and impedance results were similar in these two groups. However, there was a positive correlation between BMI and total and supine pH < 4 episodes (P = 0.002, r = 0.414; P = 0.000, r = 0.542), pH < 4 reflux time (P = 0.015, r = 0.319; P = 0.003, r = 0.403), and DeMeester score (P = 0.012, r = 0.333). CONCLUSION: Acid reflux is correlated with BMI in asymptomatic obese individuals.en_US
dc.identifier.doi10.3748/wjg.v21.i10.3030en_US
dc.identifier.endpage3034en_US
dc.identifier.issn1007-9327
dc.identifier.issn2219-2840
dc.identifier.issue10en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage3030en_US
dc.identifier.urihttps://doi.org/10.3748/wjg.v21.i10.3030
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6042
dc.identifier.volume21en_US
dc.identifier.wosWOS:000350689100021en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherBaishideng Publishing Group Incen_US
dc.relation.ispartofWorld Journal Of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectRefluxen_US
dc.subjectImpedanceen_US
dc.subjectObesityen_US
dc.subject24-h pH-metryen_US
dc.subjectBody mass indexen_US
dc.titleGastroesophageal reflux in asymptomatic obese subjects: An esophageal impedance-pH studyen_US
dc.typeArticleen_US

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