Gastroesophageal reflux in asymptomatic obese subjects: An esophageal impedance-pH study
dc.contributor.author | Akyüz, Filiz | |
dc.contributor.author | Uyanıkoğlu, Ahmet | |
dc.contributor.author | Ermiş, Fatih | |
dc.contributor.author | Arıcı, Serpil | |
dc.contributor.author | Akyüz, Ümit | |
dc.contributor.author | Baran, Bülent | |
dc.contributor.author | Gül, Nurdan | |
dc.date.accessioned | 2020-05-01T12:10:09Z | |
dc.date.available | 2020-05-01T12:10:09Z | |
dc.date.issued | 2015 | |
dc.department | DÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü | en_US |
dc.description | Baran, Bulent/0000-0001-7966-2346; Uyanikoglu, Ahmet/0000-0003-4881-5244 | en_US |
dc.description | WOS: 000350689100021 | en_US |
dc.description | PubMed: 25780302 | en_US |
dc.description.abstract | AIM: To investigate the relationship between reflux and body mass index (BMI) in the asymptomatic obese population using the impedance-pH technique. METHODS: Gastroesophageal reflux is frequent in the obese population. However, the relationship between acid reflux and BMI in asymptomatic obese people is unclear. Forty-six obese (BMI > 25 kg/m(2)) people were enrolled in this prospective study. We evaluated the demographic findings and 24-h impedance pH values of the whole group. Gas, acid (pH < 4), weak acid (pH = 4-7) and weak alkaline (pH = 7) reflux parameters were analyzed. RESULTS: The mean age of patients was 49.47 +/- 12.24 years, and half of them were men. The mean BMI was 30.64 +/- 3.95 kg/m(2) (25.14-45.58 kg/m(2)). BMI of 23 was over 30 kg/m(2). Seventeen patients had a comorbidity (hypertension, diabetes mellitus, or ischemic heart disease). Endoscopic examination revealed esophagitis in 13 of the 28 subjects (10 Grade A, 3 Grade B). The subjects were divided into two groups according to BMI (< 30 and > 30 kg/m(2)). Demographic and endoscopic findings, and impedance results were similar in these two groups. However, there was a positive correlation between BMI and total and supine pH < 4 episodes (P = 0.002, r = 0.414; P = 0.000, r = 0.542), pH < 4 reflux time (P = 0.015, r = 0.319; P = 0.003, r = 0.403), and DeMeester score (P = 0.012, r = 0.333). CONCLUSION: Acid reflux is correlated with BMI in asymptomatic obese individuals. | en_US |
dc.identifier.doi | 10.3748/wjg.v21.i10.3030 | en_US |
dc.identifier.endpage | 3034 | en_US |
dc.identifier.issn | 1007-9327 | |
dc.identifier.issn | 2219-2840 | |
dc.identifier.issue | 10 | en_US |
dc.identifier.scopusquality | Q1 | en_US |
dc.identifier.startpage | 3030 | en_US |
dc.identifier.uri | https://doi.org/10.3748/wjg.v21.i10.3030 | |
dc.identifier.uri | https://hdl.handle.net/20.500.12684/6042 | |
dc.identifier.volume | 21 | en_US |
dc.identifier.wos | WOS:000350689100021 | en_US |
dc.identifier.wosquality | Q2 | en_US |
dc.indekslendigikaynak | Web of Science | en_US |
dc.indekslendigikaynak | PubMed | en_US |
dc.indekslendigikaynak | Scopus | en_US |
dc.language.iso | en | en_US |
dc.publisher | Baishideng Publishing Group Inc | en_US |
dc.relation.ispartof | World Journal Of Gastroenterology | en_US |
dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Reflux | en_US |
dc.subject | Impedance | en_US |
dc.subject | Obesity | en_US |
dc.subject | 24-h pH-metry | en_US |
dc.subject | Body mass index | en_US |
dc.title | Gastroesophageal reflux in asymptomatic obese subjects: An esophageal impedance-pH study | en_US |
dc.type | Article | en_US |
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