Naproxen-induced fixed drug eruption: A case report

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dc.contributor.authorAkyazı, Hikmet
dc.contributor.authorBaltacı, Davut
dc.contributor.authorMungan, Sevdegül
dc.contributor.authorKara, İsmail Hamdi
dc.date.accessioned2020-04-30T23:19:28Z
dc.date.available2020-04-30T23:19:28Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionKARA, ISMAIL HAMDI/0000-0003-2022-1882; KARA, ISMAIL HAMDI/0000-0003-2022-1882en_US
dc.descriptionWOS: 000296157700016en_US
dc.descriptionPubMed: 21357631en_US
dc.description.abstractNaproxen is a non-steroidal anti-inflammatory drug (NSAID) widely used for symptomatic relief of arthritis and other painful disorders, such as dysmenorrheal. Pruritus is the most common side effect of naproxen. Fixed drug eruption (FDE) due to naproxen is a rarely reported side-effect. No previous report has declared cross-reactivity between naproxen and other propionic acid derivatives. A 28-year-old man, presented with edematous and erythematous patchy lesion along with pruritus and inflammation on lip, have been suffering since 3 hours. It started after taking naproxen 550 mg for headache. On detailed inquiry, he defined similar symptom which recurred after whenever he took naproxen. Based on clinical and histopathological findings, it is evaluated as naproxen-induced FDE. We have tested cross-reactivity between naproxen and other propionic acid derivatives, and then we obtained negative result for oral provocation test with flurbiprofen. Here, we present a case of naproxen-induced FDE of 28-year-old man, by overviewing literatures.en_US
dc.identifier.doi10.1177/0960327111400105en_US
dc.identifier.endpage1874en_US
dc.identifier.issn0960-3271
dc.identifier.issue11en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1872en_US
dc.identifier.urihttps://doi.org/10.1177/0960327111400105
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3763
dc.identifier.volume30en_US
dc.identifier.wosWOS:000296157700016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofHuman & Experimental Toxicologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectfixed drug eruptionen_US
dc.subjectnaproxenen_US
dc.subjectcross-reactivityen_US
dc.titleNaproxen-induced fixed drug eruption: A case reporten_US
dc.typeArticleen_US

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