Evaluation of serum Vitamin B12 level and related nutritional status among apparently healthy obese female individuals

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dc.contributor.authorBaltacı, Davut
dc.contributor.authorDeler, Mehmet Harun
dc.contributor.authorTürker, Yasin
dc.contributor.authorErmiş, Fatih
dc.contributor.authorIliev, Darko
dc.contributor.authorVelioğlu, Usame
dc.date.accessioned2020-05-01T12:14:53Z
dc.date.available2020-05-01T12:14:53Z
dc.date.issued2017
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000391533800018en_US
dc.descriptionPubMed: 27958255en_US
dc.description.abstractObjective: Obesity is a major public health problem and great risk for not only cardiovascular diseases but also cancer, musculoskeletal, and gynecological diseases. This study was aimed to investigate the association between serum Vitamin B12 (vitB12), body mass index (BMI), and nutritional status among obese women. Methods: This cross-sectional study enrolled consecutive female subjects. The consumptions of red meat, fish, bovine liver, egg, and mushroom were recorded. According to the Dietary Reference Intakes, the patients were categorized as insufficiency and sufficiency. Three cutoff points were defined for vitB12 status: (1) Deficiency if vitB12 is < 200 pg/mL; (2) insufficiency if vitB12 is 250-350 pg/mL, and (3) sufficient if vitB12 is >= 350 pg/mL. According to BMI, the patients were assigned to nonobese and obese groups. BMI, serum vitB12 level, consumptions of red meat, fish, bovine liver, egg, and mushroom were evaluated and compared between two groups. Results: Mean level of vitB12 was 247.8 +/- 10.4 pg/mL and significantly associated with consumption of egg (P = 0.031), bovine liver (P = 0.004), mushroom (P = 0.040), and red meat (P = 0.003). VitB12 was significantly higher in nonobese than obese group (282.5 +/- 106.8 vs. 242.5 +/- 107.5 pg/mL, P = 0.001). The ratio of vitB12 deficiency was significantly higher in obese than nonobese group (37.6% vs. 24.7%; P = 0.019). VitB12 level was negatively correlated with BMI (r = -0.155; P < 0.001), but not insulin resistance (r = -0.172; P = 0.062). Conclusion: Obesity was associated with low level of vitB12 in obese women, and more likely to be vitB12 deficient. Consumption of certain types of food contributes to increase vitB12 level.en_US
dc.identifier.doi10.4103/1119-3077.181401en_US
dc.identifier.endpage105en_US
dc.identifier.issn1119-3077
dc.identifier.issue1en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage99en_US
dc.identifier.urihttps://doi.org/10.4103/1119-3077.181401
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6388
dc.identifier.volume20en_US
dc.identifier.wosWOS:000391533800018en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherMedknow Publications & Media Pvt Ltden_US
dc.relation.ispartofNigerian Journal Of Clinical Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBody mass indexen_US
dc.subjectinsulin resistanceen_US
dc.subjectnutritionen_US
dc.subjectobesityen_US
dc.subjectVitamin B12en_US
dc.titleEvaluation of serum Vitamin B12 level and related nutritional status among apparently healthy obese female individualsen_US
dc.typeArticleen_US

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