Effects of the Degree of Obesity on Achieving Target Blood Pressure and Metabolic Deterioration in Obese Individuals: A Population-Based Study

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dc.contributor.authorÖztürk, Serkan
dc.contributor.authorBaltacı, Davut
dc.contributor.authorTürker, Yasemin
dc.contributor.authorKutlucan, Ali
dc.contributor.authorYengil, Erhan
dc.contributor.authorDeler, Mehmet Harun
dc.contributor.authorAnkaralı, Handan
dc.date.accessioned2020-05-01T09:12:04Z
dc.date.available2020-05-01T09:12:04Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAnkarali, Handan Camdeviren/0000-0002-3613-0523en_US
dc.descriptionWOS: 000329057200002en_US
dc.descriptionPubMed: 24356545en_US
dc.description.abstractBackground/Aims: This study aimed to evaluate the severity of obesity and its impact on achieving target blood pressure and metabolic derangement in obese individuals. Methods: This cross-sectional and population-based study was conducted between January and December 2012. A total of 1837 consecutive obese patients admitted to our outpatient clinic were enrolled. The anthropometric and blood pressure measurements, bioelectrical impedance fat analysis, blood sample analysis, impaired glucose status, metabolic syndrome, and insulin resistance of 1265 obese patients were compared between groups of patients separated by severity of obesity. Results: Only approximately one-third of patients with previous hypertension achieved normal blood pressure. In addition, the majority of patients without previous hypertension had higher blood pressure at the end of the study compared with baseline. The percent of patients with an impaired fasting blood glucose >= 100 mg/dL was 38.5%. The frequency of impaired glucose tolerance was 39.1% in the patients who underwent OGTT. Body mass index (BMI) was associated with impaired blood glucose, hypertension, insulin resistance, and the development of metabolic syndrome. The incidences of metabolic syndrome, insulin resistance, impaired glucose tolerance, and uncontrolled blood pressure were significantly different between groups of differing obesity severity (p<0.001, p<0.001, p=0.041, and p<0.001, respectively). Conclusion: The severity of obesity was associated with the failure to achieve target blood pressure and metabolic syndrome. Based on our data, blood pressure and metabolic parameters in obese patients should be monitored frequently and treated with caution. Copyright (C) 2013 S. Karger AG, Baselen_US
dc.identifier.doi10.1159/000355733en_US
dc.identifier.endpage539en_US
dc.identifier.issn1420-4096
dc.identifier.issn1423-0143
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage531en_US
dc.identifier.urihttps://doi.org/10.1159/000355733
dc.identifier.urihttps://hdl.handle.net/20.500.12684/5865
dc.identifier.volume37en_US
dc.identifier.wosWOS:000329057200002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofKidney & Blood Pressure Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectObesityen_US
dc.subjectTarget blood pressureen_US
dc.subjectBody mass indexen_US
dc.subjectMetabolic disordersen_US
dc.titleEffects of the Degree of Obesity on Achieving Target Blood Pressure and Metabolic Deterioration in Obese Individuals: A Population-Based Studyen_US
dc.typeArticleen_US

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