Mast cells numbers and peritumoral microvessel density of the prostatic adenocarcinomas and correlation with prognostic parameters

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dc.contributor.authorErdem, Havva
dc.contributor.authorKayıkçı, Muhammet Ali
dc.contributor.authorOktay, Murat
dc.contributor.authorUzunlar, Ali Kemal
dc.contributor.authorTekin, Ali
dc.contributor.authorŞener, Ebru
dc.contributor.authorKadıoğlu, Nilüfer
dc.date.accessioned2020-04-30T13:32:45Z
dc.date.available2020-04-30T13:32:45Z
dc.date.issued2013
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionPubMed ID: 23892847en_US
dc.description.abstractAim To determine the utility of mast cell numbers and microvascular density (MVD) in evaluating acinar type of prostatic adenocarcinoma (PCa), and to ascertain a relationship between the number of mast cells with prognostic parameters (larger tumor volume, high Gleason score, lymphovascular, perineural, seminal vesicles invasion, metastatic lymph node). Methods The study comprised 97 radical prostatectomy specimens. The paraffin sections were stained with anti-CD31, anti- CD34 and Toluidine Blue. The numbers of positive staining of cells and microvessels in 10 high-power fields were counted systematically. Results A statistically significant relationship was found between MVDn and number of MC (r=0.218 and p=0. 032). There was no correlation between age and MC and MVD (p=0.406 and p=0.671, respectively). Conclusion A correlation between mast cell number and microvascular density cannot depend on tumor angiogenesis or this relationship can be an independent parameter. More comprehensive studies could reveal relationship with prognostic parameters.en_US
dc.identifier.endpage297en_US
dc.identifier.issn1840-0132
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage293en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/425
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofMedicinski Glasniken_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCD31,CD34; Gleason score; Toluidine Blue; Tumor volumeen_US
dc.titleMast cells numbers and peritumoral microvessel density of the prostatic adenocarcinomas and correlation with prognostic parametersen_US
dc.typeArticleen_US

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