Severe Acidemia, Leukocytosis and Low Hematocrit Levels at Admission as Mortality Predictors of Elderly Intensive Care Unit Patients

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dc.contributor.authorAkbaş, Türkay
dc.contributor.authorTaşçı, Elif Şenocak
dc.contributor.authorYılmaztepe, Hafize Titiz
dc.contributor.authorSönmez, Feruze Turan
dc.contributor.authorKöş, Durdu Mehmet
dc.contributor.authorÖneç, Birgül
dc.date.accessioned2020-04-30T23:31:54Z
dc.date.available2020-04-30T23:31:54Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000500544100003en_US
dc.description.abstractAim: Rapid prediction of prognosis is helpful in reflecting the disease severity and patient mortality. This is especially important in critically ill elderly patients who have high mortality risk. This study aimed to investigate the effects of admission laboratory results and medical histories on the prediction of prognosis in critically ill elderly patients. Material and Methods: Patients who were >= 65 years and admitted to a medical intensive care unit (ICU) between 2011 and 2013 were retrospectively analyzed. Results: The study included 449 patients and mortality rate was 47.4%. Nonsurvivors had lower pH, HCO3 and albumin levels, and lower hematocrit and platelet counts, but higher aspartate aminotransferase, alanine aminotransferase, C-reactive protein (CRP), creatinine, phosphorus, magnesium and bilirubin levels, and higher leukocyte count than survivors. The rates of chronic kidney disease, being in a bedridden state and having cardiopulmonary resuscitation (CPR) before ICU admission were significantly high in nonsurvivors. Multivariate analysis showed that pH <7.20, albumin <= 2 gr/dL, low hematocrit and high CRP levels, high leukocyte count, bedridden state, and CPR were mortality predictors. After including the admission diagnoses and endotracheal intubation into the model, pH <7.20 (odds ratio [OR], 4.31; 95% confidence interval [CI], 1.59-11.70), albumin <= 2 gr/dL (OR, 3.61; 95% CI, 0.99-13.03), hematocrit level (OR, 0.94; 95% CI, 0.91-0.99) and leukocyte count (OR 1.06; 95% CI, 1.01-1.11) retained their prognostic importance for mortality. Conclusions: Severe acidemia, low albumin and hematocrit levels, and high leukocyte count at admission help clinicians to foresee the prognosis in severely ill elderly patients. They keep their importance even in the presence of other fundamental mortality predictors.en_US
dc.identifier.doi10.33381/dcbybd.2019.2015en_US
dc.identifier.endpage52en_US
dc.identifier.issn1309-1689
dc.identifier.issn1309-6222
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage47en_US
dc.identifier.urihttps://doi.org/10.33381/dcbybd.2019.2015
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4526
dc.identifier.volume10en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTurkish Soc Medical & Surgical Intensive Care Medicineen_US
dc.relation.ispartofJournal Of Medical And Surgical Intensive Care Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectComorbidityen_US
dc.subjectelderly patientsen_US
dc.subjecthypoalbuminemiaen_US
dc.subjectintensive care uniten_US
dc.subjectpHen_US
dc.subjectprognosisen_US
dc.titleSevere Acidemia, Leukocytosis and Low Hematocrit Levels at Admission as Mortality Predictors of Elderly Intensive Care Unit Patientsen_US
dc.typeArticleen_US

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