Relationship between blood pressure levels and bone mineral density in postmenopausal Turkish women

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dc.contributor.authorYazıcı, Selma
dc.contributor.authorYazıcı, Mehmet
dc.contributor.authorKorkmaz, Uğur
dc.contributor.authorErkan, Melih Engin
dc.contributor.authorBaki, Ali Erdem
dc.contributor.authorErden, İsmail
dc.contributor.authorAtaoğlu, Safinaz
dc.date.accessioned2020-04-30T23:31:36Z
dc.date.available2020-04-30T23:31:36Z
dc.date.issued2011
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000290915100012en_US
dc.descriptionPubMed: 22291766en_US
dc.description.abstractIntroduction: We investigated the association between bone mineral density (BMD) detected by dual-energy X-ray absorptiometric (DXA) method and blood pressure (BP) in a large sample of postmenopausal women. Material and methods: The current study was based on a retrospective analysis of 586 postmenopausal women with a mean age of 60.8 +/- 8.8 years, who were screened for osteopenia or osteoporosis by DXA. Patients with hypertension (HT, n = 306) were compared with normotensive (NT, n = 290) individuals. Bone mineral density results for the femur neck and spine were classified into 3 groups according to World Health Organization criteria: normal (T score > -1.0 SD), osteopenia (T score -1.0 to -2.5 SD) and osteoporosis (T score <-2.5 SD). Patients with osteopenia or osteoporosis (T score < -1.0 SD) were grouped as having low bone mass (LBM). Results: There were no significant differences in femur T score, femur BMD, femur Z score, spinal T score, spinal BMD and spinal Z score between hypertensive and normotensive groups. The group of patients with low bone mass calculated from femur T scores had higher age, systolic BP, duration of hypertension and duration of menopause, but lower BMI. Similarly, patients with low spine BMD had higher age and duration of menopause, but lower BMI. Linear regression analysis showed a significant correlation between systolic BP and femur BMD and T score values. Furthermore, logistic regression analysis revealed that hypertension is an independent predictor of spinal osteopenia and osteoporosis. Conclusions: The presence of hypertension is an independent predictor of spinal low bone density in Turkish women after menopause.en_US
dc.identifier.doi10.5114/aoms.2011.22077en_US
dc.identifier.endpage270en_US
dc.identifier.issn1734-1922
dc.identifier.issue2en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage264en_US
dc.identifier.urihttps://doi.org/10.5114/aoms.2011.22077
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4349
dc.identifier.volume7en_US
dc.identifier.wosWOS:000290915100012en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTermedia Publishing House Ltden_US
dc.relation.ispartofArchives Of Medical Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectblood pressureen_US
dc.subjectbone mineral densityen_US
dc.subjectdual-energy X-ray absorptiometricen_US
dc.titleRelationship between blood pressure levels and bone mineral density in postmenopausal Turkish womenen_US
dc.typeArticleen_US

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