Obstructive Sleep Apnea Syndrome in Adult Patients with Asthma

Basit Öğe Kaydı
dc.contributor.authorAnnakkaya, Ali Nihat
dc.contributor.authorAkın, Neşe
dc.contributor.authorBalbay, Ege
dc.contributor.authorArbak, Peri Meram
dc.contributor.authorToru, Ümran
dc.date.accessioned2020-04-30T23:19:48Z
dc.date.available2020-04-30T23:19:48Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionAnnakkaya, Ali Nihat N/0000-0002-7661-8830; Balbay, Ege Gulec/0000-0002-1557-7019en_US
dc.descriptionWOS: 000300538400009en_US
dc.description.abstractObjective and Introduction: Previous epidemiological studies have shown respiratory system diseases and obstructive sleep apnea syndrome (OSAS) to be frequently concomitant, and co-occurrence of OSAS with respiratory system disease increased the severity and complications of underlying lung disease. It is known that symptoms associated with asthma are generally more severe at nights. Obesity is a common risk factor for two prevalent disorders, namely asthma and obstructive sleep apnea syndrome, which are commonly observed in the society and are important at both individual and social levels. Similarly, anatomical and functional abnormalities of the upper airways and gastroesophageal reflux are other associated factors. Moreover, since upper airways, which is the focus of physiopathology in OSAS, is an important area affected also in asthma, it leads to research evaluating possible interactions of these two diseases with a mutual pathway in etiology. The objective of this study was to investigate the prevalence of OSAS in patients with asthma and its effect on the severity and the management of asthma. Material and Methods: In this study, 50 consecutive adult asthma patients (35 female and 15 male) who applied to the Department of Chest Diseases and accepted to participate in the study, were included. All of these patients underwent full overnight polysomnography. Results: The overall prevalence of OSAS was 40% (moderate and severe OSAS: 16%) in asthma patients. However, no significant difference could be determined between OSAS prevalence, based on the asthma severity. OSAS was determined at rates of; 52.9% (9/17) in full control asthma patients, 40.9% (9/22) in those with partial control, and 18.2% (2/11) in patients with no control. As better control levels were provided for asthma, prevalence of OSAS increased, however the differences were not statistically significant (p=0.185). Between OSAS severity and asthma control level, a weak reverse correlation was determined (p=0.05, r=0.279). In all asthma patients with OSAS, snoring was present (negative predictive value 100%). In asthma patients with habitual snoring, witnessed apnea and daytime sleepiness symptoms, OSAS prevalence was significantly higher compared to those with no symptoms. As concomitance of major symptoms increased, OSAS prevalence also increased significantly (p<0.05). As neck circumference and body mass index of patients with asthma increased, apnea-hypopnea index and OSAS severity significantly increased (p<0.05). A significantly positive correlation was determined between triceps fat thickness and asthma severity (p=0.003, r=0.563). Conclusions: Compared to the regular population, among adult asthma patients, OSAS prevalence was much higher. Especially asthma patients who are obese and have wide neck circumference should be examined regarding OSAS symptoms. In the presence of major OSAS symptoms, polysomnographic examination should definitely be conducted. The lack of snoring can be an important criterion in the exclusion of OSAS in asthma. Further studies are necessary in order to produce concomitance, interaction and long-term results of these two diseases.en_US
dc.identifier.endpage64en_US
dc.identifier.issn1840-2291
dc.identifier.issn1986-8103
dc.identifier.issue1en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage53en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/3856
dc.identifier.volume6en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherDrunpp-Sarajevoen_US
dc.relation.ispartofHealthmeden_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectasthmaen_US
dc.subjectsleep apneaen_US
dc.subjectobesityen_US
dc.subjectsnoringen_US
dc.subjectobstructive sleep apnea syndromeen_US
dc.subjectOSASen_US
dc.titleObstructive Sleep Apnea Syndrome in Adult Patients with Asthmaen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Makale Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu