Royal Jelly in modern biomedicine: A review of its bioactive constituents and health benefits

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dc.contributor.authorSonmez, Emine
dc.date.accessioned2026-07-01T11:40:01Z
dc.date.available2026-07-01T11:40:01Z
dc.date.issued2025
dc.departmentDüzce Üniversitesi
dc.description.abstractRoyal jelly (RJ) is a nutrient-rich secretion produced by honeybees, known for its wide range of physiological and pharmacological effects. Comprising a complex mixture of proteins, lipids, vitamins, minerals, polyphenols, and hormones, RJ exhibits significant therapeutic potential across multiple domains of health. Key bioactive constituents such as 10-hydroxy-2(E)-decenoic acid (10-HDA), major royal jelly proteins (MRJPs), royalisin, apisimin, and jelleins are central to its antimicrobial, anti-inflammatory, antioxidant, immunomodulatory, anticancer wound-healing, longevity-promoting, and anti-aging effects. By supporting tissue repair and regeneration, RJ shows promise for medical and therapeutic applications. This review highlights the molecular mechanisms behind RJ's diverse biological activities and underscores its potential as a multifunctional therapeutic agent. The findings emphasize the need for further clinical research to validate RJ's efficacy and integrate it into evidencebased medical practice.
dc.identifier.doi10.1016/j.jff.2025.107062
dc.identifier.issn1756-4646
dc.identifier.issn2214-9414
dc.identifier.scopus2-s2.0-105020960800
dc.identifier.scopusqualityQ1
dc.identifier.urihttps://doi.org/10.1016/j.jff.2025.107062
dc.identifier.urihttps://hdl.handle.net/20.500.12684/23584
dc.identifier.volume134
dc.identifier.wosWOS:001600207300001
dc.identifier.wosqualityQ2
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.institutionauthorSonmez, Emine
dc.language.isoen
dc.publisherElsevier
dc.relation.ispartofJournal of Functional Foods
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20260623
dc.subjectRoyal Jelly
dc.subjectBioactive Components
dc.subjectBiological Functions
dc.subjectAntimicrobial Activity
dc.subjectAntioxidant Effect
dc.subjectAnticancer Activity
dc.titleRoyal Jelly in modern biomedicine: A review of its bioactive constituents and health benefits
dc.typeArticle

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