Royal Jelly in modern biomedicine: A review of its bioactive constituents and health benefits

Küçük Resim Yok

Tarih

2025

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Elsevier

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Royal jelly (RJ) is a nutrient-rich secretion produced by honeybees, known for its wide range of physiological and pharmacological effects. Comprising a complex mixture of proteins, lipids, vitamins, minerals, polyphenols, and hormones, RJ exhibits significant therapeutic potential across multiple domains of health. Key bioactive constituents such as 10-hydroxy-2(E)-decenoic acid (10-HDA), major royal jelly proteins (MRJPs), royalisin, apisimin, and jelleins are central to its antimicrobial, anti-inflammatory, antioxidant, immunomodulatory, anticancer wound-healing, longevity-promoting, and anti-aging effects. By supporting tissue repair and regeneration, RJ shows promise for medical and therapeutic applications. This review highlights the molecular mechanisms behind RJ's diverse biological activities and underscores its potential as a multifunctional therapeutic agent. The findings emphasize the need for further clinical research to validate RJ's efficacy and integrate it into evidencebased medical practice.

Açıklama

Anahtar Kelimeler

Royal Jelly, Bioactive Components, Biological Functions, Antimicrobial Activity, Antioxidant Effect, Anticancer Activity

Kaynak

Journal of Functional Foods

WoS Q Değeri

Q2

Scopus Q Değeri

Q1

Cilt

134

Sayı

Künye