The Relationship of Headache with Inflammatory Serum Parameters and Disease Severity in COVID-19 Patients

Basit Öğe Kaydı
dc.contributor.authorAlay, Handan
dc.contributor.authorBilge, Nuray
dc.contributor.authorCan, Fatma Kesmes
dc.date.accessioned2023-04-10T20:19:33Z
dc.date.available2023-04-10T20:19:33Z
dc.date.issued2020
dc.departmentRektörlük, Rektörlüğe Bağlı Birimler, Düzce Üniversitesi Dergilerien_US
dc.description.abstractAim: Most of the coronavirus disease 2019 (COVID-19) patients have respiratory symptoms;however, various neurological symptoms, such as headache, can be seen. Thepathophysiological mechanism of headache in COVID-19 is unknown completely. In ourstudy, we aimed to investigate the relationship between headache and inflammatory markersand disease severity in COVID-19 patients.Material and Methods: Two hundred and three hospitalized patients with a polymerase chainreaction (PCR)-confirmed COVID-19 diagnosis between 15 March and 01 June 2020 wereretrospectively investigated. A total of 62 patients with headache symptoms (n=31) andwithout headache symptoms (n=31), who were age and gender-matched, were included in thestudy. The demographic characteristics, inflammatory serum parameters,neutrophil/lymphocyte ratio (NLR), C-reactive protein (CRP)/albumin ratio (CAR),hospitalization times, and disease severity were determined.Results: Of the 203 COVID-19 patients, 36 (17.7%) had a headache, and it was the fourthmost common symptom. Headache accompanied other symptoms in all patients. Of thepatients with headache, 14 (45.2%) were female, 17 (54.8%) were male, and the mean age was37.74±16.65 years. In our COVID-19 patients, the neutrophil count, NLR, CRP, CAR weresignificantly higher, and hospital stay was longer in patients with headache than those withoutheadache (p=0.023, p=0.041, p=0.034, p=0,048 and p=0.049, respectively).Conclusion: As a result, the increased inflammatory response may play a role in thepathogenesis of headache in COVID-19 patients. Our study is the first study that evaluated therelationship between headache symptom and inflammation in COVID-19 patients. Furtherresearch is needed on this subject.en_US
dc.identifier.doi10.18678/dtfd.776731
dc.identifier.endpage50en_US
dc.identifier.issn1307-671X
dc.identifier.issueS1en_US
dc.identifier.startpage44en_US
dc.identifier.trdizinid386555en_US
dc.identifier.urihttp://doi.org/10.18678/dtfd.776731
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/386555
dc.identifier.urihttps://hdl.handle.net/20.500.12684/11409
dc.identifier.volume22en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofDüzce Tıp Fakültesi Dergisi
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleThe Relationship of Headache with Inflammatory Serum Parameters and Disease Severity in COVID-19 Patientsen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
11409.pdf
Boyut:
408.53 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Düzce Tıp Fakültesi Dergisi Koleksiyonu