The Results of Liver Transplantation Performed In a Single Center Due To Hepatocellular Carcinoma

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dc.authoridSahin, Dilek/0000-0001-8567-9048en_US
dc.authoridSahin, Dilek/0000-0003-0865-7763en_US
dc.authorwosidSahin, Dilek/ABE-3511-2020en_US
dc.authorwosidSahin, Dilek/GXH-7191-2022en_US
dc.contributor.authorAslan, Serdar
dc.contributor.authorYazar, Serafettin
dc.contributor.authorKargi, Ahmet
dc.contributor.authorKurnaz, Eray
dc.contributor.authorSahin, Dilek
dc.contributor.authorPeker, Kemal
dc.contributor.authorAstarcioglu, Ibrahim
dc.date.accessioned2024-08-23T16:03:50Z
dc.date.available2024-08-23T16:03:50Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractObjective: Hepatocellular cancer (HCC) is the most common malignancy of the hepatobiliary system. There are significant differences in the global spread of HCC. It is the major cause of death in patients with cirrhosis. Its molecular pathogenesis is highly complex and heterogeneous. Major risk factors for the development of HCC are chronic hepatitis B virus (HBV) infection, chronic hepatitis C virus (HCV) infection and alcohol related liver cirrhosis. Hepatocellular cancer is rarely seen in the first 4 decades of life, except in communities where HBV infection is hyperendemic.Methods: The study was conducted by retrospectively scanning the files of 204 patients diagnosed with HCC who applied to Organ Transplantation Center between 21.09.2014 and 13.04.2019. Patients were transplanted liver by being classified according to Milan criteria, San Francisco [University of California San Francisco (UCSF)] criteria, and Barcelona Clinic Liver Cancer (BCLC) criteria.Results: The median age of the patients was 58.03 (range 31 to 72). 170 of the patients were men and 34 of them were female. Liver transplantation (LT) was performed from cadaveric donors to 31 patients and from living donors to 173 patients. There is a significant relationship between the life span of the patients and their gender. Female patients have a longer life expectancy [t (202) = 2.963, p =0.003]. A significant relationship was found between life expectancy and surgical classification [F (3) = 3.008, (p =0.031)].Conclusions: In patients diagnosed with HCC and undergoing LT; the gender being female and the classification method before transplantation affect life expectancy.en_US
dc.identifier.doi10.18521/ktd.1201669
dc.identifier.endpage174en_US
dc.identifier.issn1309-3878
dc.identifier.issue2en_US
dc.identifier.startpage169en_US
dc.identifier.trdizinid1185727en_US
dc.identifier.urihttps://doi.org/10.18521/ktd.1201669
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1185727
dc.identifier.urihttps://hdl.handle.net/20.500.12684/13940
dc.identifier.volume15en_US
dc.identifier.wosWOS:001029516200002en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherDuzce Univ, Fac Medicineen_US
dc.relation.ispartofKonuralp Tıp Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTransplantationen_US
dc.subjectLiveren_US
dc.subjectHepatocellular Carcinomaen_US
dc.subjectHepatic Resectionen_US
dc.subjectMechanismsen_US
dc.subjectMulticenteren_US
dc.subjectMultipleen_US
dc.subjectHccen_US
dc.subjectCmen_US
dc.titleThe Results of Liver Transplantation Performed In a Single Center Due To Hepatocellular Carcinomaen_US
dc.typeArticleen_US

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