The relationship between attachment and serum oxytocin and heat shock protein-70 levels in adolescents of parents with schizophrenia and bipolar disorder

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dc.authorscopusid57215535475en_US
dc.authorscopusid56078893600en_US
dc.authorscopusid58525036700en_US
dc.authorscopusid15077376700en_US
dc.authorscopusid6507061445en_US
dc.contributor.authorÖz, B.O.
dc.contributor.authorAlpay, M.
dc.contributor.authorKaban, Ş.Ö.
dc.contributor.authorSungur, M.A.
dc.contributor.authorAtao?lu, A.
dc.date.accessioned2024-08-23T16:07:29Z
dc.date.available2024-08-23T16:07:29Z
dc.date.issued2023en_US
dc.departmentDüzce Üniversitesien_US
dc.description.abstractBackground: The aim of this study was to evaluate serum heat shock protein 70 (HSP70) and oxytocin levels, attachment and perceived social support levels in adolescents with parental bipolar disorder (BD) and Schizophrenia (SCZ). Subjects and Methods: This study included 9 adolescents with SCZ parents, 30 adolescents with BD parents and 31 healthy adolescents. Brief Symptom Inventory (BSI), Relationship Scale Questionnaire-Adolescent Form (RSQ-A) and Multidimensional Scale of Perceived Social Support (MSPSS) were administered to all participants. In addition, serum HSP-70 and oxytocin levels were evaluated. Results: There was no significant difference between the groups in terms of attachment style, psychiatric symptoms and perceived social support. Serum HSP-70 levels were found to be lower in adolescents whose parents had BD. Serum oxytocin levels of the SCZ group were significantly lower than those of the BD group. Conclusions: HSP-70 level was found to be lower in adolescents with BD parents. Oxytocin level was found to be lower in adolescents with SCZ parents. These findings suggest that HSP-70 and oxytocin may be a marker of early life stress in adolescents with parental psychopathology. However, studies are needed to evaluate the relationship between attachment, oxytocin and HSP-70 in adolescents exposed to parental psychopathology in early life. © 2023 Medicinska naklada & Pro mente, Zagreb, Croatia.en_US
dc.description.sponsorshipDüzce University Scientific Research Project Coordinator Unit, (2021.04.03.1246)en_US
dc.identifier.doi10.24869/psyd.2023.199
dc.identifier.endpage209en_US
dc.identifier.issn0353-5053
dc.identifier.issue2en_US
dc.identifier.pmid37480307en_US
dc.identifier.scopus2-s2.0-85166964044en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage199en_US
dc.identifier.urihttps://doi.org/10.24869/psyd.2023.199
dc.identifier.urihttps://hdl.handle.net/20.500.12684/14674
dc.identifier.volume35en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherMedicinska Naklada Zagreben_US
dc.relation.ispartofPsychiatria Danubinaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectadolescentsen_US
dc.subjectAttachmenten_US
dc.subjectbipolar disorderen_US
dc.subjectheat shock protein-70en_US
dc.subjectoxytocinen_US
dc.subjectAdolescenten_US
dc.subjectBipolar Disorderen_US
dc.subjectHSP70 Heat-Shock Proteinsen_US
dc.subjectHumansen_US
dc.subjectOxytocinen_US
dc.subjectParentsen_US
dc.subjectSchizophreniaen_US
dc.subjectantidepressant agenten_US
dc.subjectheat shock protein 70en_US
dc.subjectmethylphenidateen_US
dc.subjectneuroleptic agenten_US
dc.subjectoxytocinen_US
dc.subjectheat shock protein 70en_US
dc.subjectoxytocinen_US
dc.subjectadolescenten_US
dc.subjectadulten_US
dc.subjectanxietyen_US
dc.subjectanxiety disorderen_US
dc.subjectArticleen_US
dc.subjectattention deficit hyperactivity disorderen_US
dc.subjectbipolar disorderen_US
dc.subjectBrief Symptom Inventoryen_US
dc.subjectchilden_US
dc.subjectconduct disorderen_US
dc.subjectcontrolled studyen_US
dc.subjectdepressionen_US
dc.subjectemotional attachmenten_US
dc.subjectfamilyen_US
dc.subjectfemaleen_US
dc.subjectfrienden_US
dc.subjecthostilityen_US
dc.subjecthumanen_US
dc.subjectmajor depressionen_US
dc.subjectmaleen_US
dc.subjectMultidimensional Scale of Perceived Social Supporten_US
dc.subjectnegative valenceen_US
dc.subjectoxytocin blood levelen_US
dc.subjectprotein blood levelen_US
dc.subjectquestionnaireen_US
dc.subjectRelationship Scale Questionnaire Adolescent Formen_US
dc.subjectschizophreniaen_US
dc.subjectsocial supporten_US
dc.subjectsomatizationen_US
dc.subjectbipolar disorderen_US
dc.subjectchild parent relationen_US
dc.subjectmetabolismen_US
dc.subjectpsychologyen_US
dc.subjectschizophreniaen_US
dc.titleThe relationship between attachment and serum oxytocin and heat shock protein-70 levels in adolescents of parents with schizophrenia and bipolar disorderen_US
dc.typeArticleen_US

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