The relationship between attachment and serum oxytocin and heat shock protein-70 levels in adolescents of parents with schizophrenia and bipolar disorder
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medicinska Naklada Zagreb
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: The aim of this study was to evaluate serum heat shock protein 70 (HSP70) and oxytocin levels, attachment and perceived social support levels in adolescents with parental bipolar disorder (BD) and Schizophrenia (SCZ). Subjects and Methods: This study included 9 adolescents with SCZ parents, 30 adolescents with BD parents and 31 healthy adolescents. Brief Symptom Inventory (BSI), Relationship Scale Questionnaire-Adolescent Form (RSQ-A) and Multidimensional Scale of Perceived Social Support (MSPSS) were administered to all participants. In addition, serum HSP-70 and oxytocin levels were evaluated. Results: There was no significant difference between the groups in terms of attachment style, psychiatric symptoms and perceived social support. Serum HSP-70 levels were found to be lower in adolescents whose parents had BD. Serum oxytocin levels of the SCZ group were significantly lower than those of the BD group. Conclusions: HSP-70 level was found to be lower in adolescents with BD parents. Oxytocin level was found to be lower in adolescents with SCZ parents. These findings suggest that HSP-70 and oxytocin may be a marker of early life stress in adolescents with parental psychopathology. However, studies are needed to evaluate the relationship between attachment, oxytocin and HSP-70 in adolescents exposed to parental psychopathology in early life. © 2023 Medicinska naklada & Pro mente, Zagreb, Croatia.
Açıklama
Anahtar Kelimeler
adolescents, Attachment, bipolar disorder, heat shock protein-70, oxytocin, Adolescent, Bipolar Disorder, HSP70 Heat-Shock Proteins, Humans, Oxytocin, Parents, Schizophrenia, antidepressant agent, heat shock protein 70, methylphenidate, neuroleptic agent, oxytocin, heat shock protein 70, oxytocin, adolescent, adult, anxiety, anxiety disorder, Article, attention deficit hyperactivity disorder, bipolar disorder, Brief Symptom Inventory, child, conduct disorder, controlled study, depression, emotional attachment, family, female, friend, hostility, human, major depression, male, Multidimensional Scale of Perceived Social Support, negative valence, oxytocin blood level, protein blood level, questionnaire, Relationship Scale Questionnaire Adolescent Form, schizophrenia, social support, somatization, bipolar disorder, child parent relation, metabolism, psychology, schizophrenia
Kaynak
Psychiatria Danubina
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
35
Sayı
2
