Fungal agents as a cause of surgical wound infections: An overview of host factors

dc.contributor.authorKaya, Demet
dc.contributor.authorAğartan, Canan Aldırmaz
dc.contributor.authorYücel, Muhterem
dc.date.accessioned2020-05-01T12:10:07Z
dc.date.available2020-05-01T12:10:07Z
dc.date.issued2007
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000250267600003en_US
dc.descriptionPubMed: 26110365en_US
dc.description.abstractMicrobial virulence and host resistance are the determinants of the surgical infections. Bacteria are responsible for the majority of cases, but fungi are rare. The aim of this study was to evaluate the fungi causing surgical infections and discuss host factors predisposing the infection. Methods. A total of 824 surgical wound specimens had been evaluated. The specimens were cultured using 5% sheep blood, Sabouraud Dextrose, and Eosin methylene blue agars and the isolates were identified by classical methods and API identification system. Results. Growth was obtained in 455 (55.2%) out of 824 specimens. Nine (2%) of the agents of surgical infections were yeasts: Candida albicans was isolated in 5 (55.6%), C tropicalis in 3 (33.3%), and C glabrata in 1 (11.1%) specimen(s). Examining the characteristics of the patients, fungal infection could be explained with the presence of at least I predisposing factor. Immunosuppression was closely related with fungal growth. Conclusion. Predisposing factors impairing the immune system were detected in most of the patients showing the possibility of onset of fungal, predominantly Candidal infections. It is important for clinicians to be aware of fungal infections that may develop in this group under risk, particularly after surgery and all Candida species isolated from high-risk patients should be identified to species level, as non-albicans strains are often associated with resistance to antifungal agents.en_US
dc.identifier.endpage222en_US
dc.identifier.issn1044-7946
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage218en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12684/6022
dc.identifier.volume19en_US
dc.identifier.wosWOS:000250267600003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherH M P Communicationsen_US
dc.relation.ispartofWounds-A Compendium Of Clinical Research And Practiceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleFungal agents as a cause of surgical wound infections: An overview of host factorsen_US
dc.typeArticleen_US

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