Assessment of the frequency of deep venous thromboembolism in obstructive sleep apnea syndrome

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dc.contributor.authorBahar, Yağmur
dc.contributor.authorAnnakkaya, Ali Nihat
dc.contributor.authorŞen, Çiğdem
dc.contributor.authorOktay, Mehtap
dc.contributor.authorAytekin, Fuat
dc.contributor.authorBalbay, Öner Abidin
dc.date.accessioned2020-04-30T22:39:49Z
dc.date.available2020-04-30T22:39:49Z
dc.date.issued2019
dc.departmentDÜ, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000482895400001en_US
dc.descriptionPubMed: 31437086en_US
dc.description.abstractThe present study aimed to investigate the frequency of deep venous thrombosis (DVT) among patients with obstructive sleep apnea syndrome (OSAS). Patients who referred the preliminary diagnosis of OSAS were included in this study. D-dimer levels of all patients were measured, and D-dimer (+) patients were evaluated by Doppler USG of the lower-extremity. Mean age of the patient group was 52 +/- 12 years and 31.8% (76/239) were women. The rate of D-dimer positivity among severe-OSAS cases (15/85) was significantly higher compared to the rest (13/154) (17.6% and 8.4%, respectively; p = 0.034). The risk of D-dimer positivity was elevated by 2.3 folds in severe-OSAS cases (OR: 2,324, 95% confidence interval: 1.048-5.152). Among 28 D-dimer (+) cases, 4 (14.2%) had DVT as demonstrated by USI of the lower-extremity. All four cases with DVT had severe OSAS. D-dimer was positive in 17.6% (15/85) of all severe OSAS cases. DVT was diagnosed in 4.7% (4/85) of severe-OSAS cases. DVT frequency was 26.6% (4/15) in D-dimer (+) severe-OSAS. Findings of this study indicate that severe-OSAS can be a significant risk factor for DVT. Additionally, data obtained in this study underline the benefits of questioning severe-OSAS patients with respect to DVT symptoms, investigating D-dimer levels and evaluating D-dimer (+) severe-OSAS cases for DVT prophylaxis.en_US
dc.identifier.doi10.1080/13685538.2019.1654451en_US
dc.identifier.issn1368-5538
dc.identifier.issn1473-0790
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1080/13685538.2019.1654451
dc.identifier.urihttps://hdl.handle.net/20.500.12684/2833
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofAging Maleen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSleep apneaen_US
dc.subjectobstructive sleep apneaen_US
dc.subjectobstructive sleep apnea syndromeen_US
dc.subjectdeep venous thrombosisen_US
dc.subjectD-dimeren_US
dc.titleAssessment of the frequency of deep venous thromboembolism in obstructive sleep apnea syndromeen_US
dc.typeArticleen_US

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