The Effect of Blood and Seminal Plasma Heavy Metal and Trace Element Levels on Sperm Quality

dc.contributor.authorKahraman, Salih
dc.contributor.authorHassa, Hikmet
dc.contributor.authorKarataş, Ahmet
dc.contributor.authorIlgın, Halil
dc.date.accessioned2020-04-30T23:32:51Z
dc.date.available2020-04-30T23:32:51Z
dc.date.issued2012
dc.departmentDÜ, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümüen_US
dc.descriptionWOS: 000314145000010en_US
dc.description.abstractObjective: Infertility is shown in approximately 10-15% of the couples. Male infertility is responsible for at least 50% of them. In these infertile couples, male is responsible alone in 30% while male and female are responsible together in 20%. The semen analysis is the first laboratory test which should be done to evaluate the male infertility. Heavy metals and trace elements affect sperm production, motility and morphology. The aim of this study is to determine zinc, copper, lead and cadmium levels in blood and seminal samples of men and to evaluate their relationship with sperm quality parameters. Material and Methods: Forty-two men with abnormal sperm quality parameters and 10 control subjects were included in the study. Zinc, copper, cadmium and lead levels were measured in blood and semen. The results were compared. Results: Lead levels in blood, cadmium levels both in blood and seminal plasma were significantly higher in men with abnormal sperm analyses (p<0.05). There was a positive correlation between seminal plasma zinc level and sperm count, motility and morphology (p<0.001) and between seminal plasma copper level and sperm count and morphology (p<0.05). There was a negative correlation between lead level and sperm count, motility and morphology (p<0.001). Likewise, there was a negative correlation between blood cadmium level and sperm motility and morphology (p<0.05) and between seminal plasma cadmium level and sperm motility (p<0.05). Conclusion: Zinc and copper affect sperm quality positively whereas lead and cadmium shows a negative effect. Exposure to heavy metals is an important etiology in the male infertility problem and should be treated seriously.en_US
dc.identifier.doi10.5336/medsci.2011-26578en_US
dc.identifier.endpage1568en_US
dc.identifier.issn1300-0292
dc.identifier.issn2146-9040
dc.identifier.issue6en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage1560en_US
dc.identifier.urihttps://doi.org/10.5336/medsci.2011-26578
dc.identifier.urihttps://hdl.handle.net/20.500.12684/4833
dc.identifier.volume32en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherOrtadogu Ad Pres & Publ Coen_US
dc.relation.ispartofTurkiye Klinikleri Tip Bilimleri Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSmokingen_US
dc.subjectmetalsen_US
dc.subjectheavyen_US
dc.subjecttrace elementsen_US
dc.subjectinfertilityen_US
dc.subjectmaleen_US
dc.titleThe Effect of Blood and Seminal Plasma Heavy Metal and Trace Element Levels on Sperm Qualityen_US
dc.typeArticleen_US

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